Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes
Paris J (2019)
Bielefeld: Universität Bielefeld.
Bielefelder E-Dissertation | Englisch
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PhD thesis JP 062019.pdf
6.33 MB
Autor*in
Paris, Juraj
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Abstract / Bemerkung
Among several achievements realised throughout this research, the highlight is the use of Deep eutectic solvents for one-pot chemoenzymatic cascades. Amine transaminases and alcohol dehydrogenases displayed praiseworthy performances in these neoteric solvents for the synthesis of bulky chiral compounds.
Besides the broadening of the substrate scope, a variety of of different enzymes has been tested for both cascade reactions. These results emphasize the value of nature’s biodiversity as an ever-increasing source of new genomes and metagenomes to identify unprecedented catalytic activities which can lead to novel robust biocatalysts. Furthermore medium engineering was demonstrated to be a valuable solution for the optimisation of chemical transformations and biocatalytic reactions with the possibility to overcome a set of hurdles and and reach improvement of the overall process.
Jahr
2019
Urheberrecht / Lizenzen
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https://pub.uni-bielefeld.de/record/2938994
Zitieren
Paris J. Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Bielefeld: Universität Bielefeld; 2019.
Paris, J. (2019). Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Bielefeld: Universität Bielefeld.
Paris, Juraj. 2019. Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Bielefeld: Universität Bielefeld.
Paris, J. (2019). Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Bielefeld: Universität Bielefeld.
Paris, J., 2019. Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes, Bielefeld: Universität Bielefeld.
J. Paris, Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes, Bielefeld: Universität Bielefeld, 2019.
Paris, J.: Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Universität Bielefeld, Bielefeld (2019).
Paris, Juraj. Combination of Suzuki cross-coupling reaction and biocatalysis in one-pot cascade processes. Bielefeld: Universität Bielefeld, 2019.
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PhD thesis JP 062019.pdf
6.33 MB
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