- AutorIn
- Roman R. Stocsits
- Ivo L. Hofacker
- Claudia Fried
- Peter F. Stadler
- Titel
- Multiple sequence alignments of partially coding nucleic acid sequences
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-319132
- Quellenangabe
- BMC Bioinformatics Erscheinungsort: London
Verlag: BioMed Central
Erscheinungsjahr: 2005
Jahrgang: 6
ISSN: 1471-2105
Artikelnummer: 160 - Erstveröffentlichung
- 2005
- Abstract (EN)
- High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, however, exhibit a much larger sequence heterogeneity compared to their encoded protein sequences due to the redundancy of the genetic code. It is desirable, therefore, to make use of the amino acid sequence when aligning coding nucleic acid sequences. In many cases, however, only a part of the sequence of interest is translated. On the other hand, overlapping reading frames may encode multiple alternative proteins, possibly with intermittent non-coding parts. Examples are, in particular, RNA virus genomes.
- Freie Schlagwörter (EN)
- Biochemistry, Evolutionary biology, RNA, DNA, Nucleic acid sequence
- Klassifikation (DDC)
- 572.8
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-319132
- Veröffentlichungsdatum Qucosa
- 16.10.2018
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch