Pitfalls in microcystin extraction and recovery from human blood serum

Heussner, Alexandra H.; Altaner, Stefan; Kamp, Lisa; Rubio, Fernando; Dietrich, Daniel R.

Pitfalls in microcystin extraction and recovery from human blood serum

Dateien

Dietrich_0-267902.pdfGröße: 542.05 KBDownloads: 554

Datum

2014

Autor:innen

Heussner, Alexandra H.

Altaner, Stefan

Kamp, Lisa

Rubio, Fernando

Dietrich, Daniel R.

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Chemico-Biological Interactions. 2014, 223, pp. 87-94. ISSN 0009-2797. eISSN 1872-7786. Available under: doi: 10.1016/j.cbi.2014.08.010

Zusammenfassung

Microcystins (MCs) contaminate water bodies due to cyanobacterial blooms all over the world, leading to frequent exposure of humans to MCs through consumption of meat, fish, seafood, blue-green algal products and water, accidental ingestion of contaminated water and scum during recreational activities and inhalation of cyanobacterial aerosols. For monitoring of human exposure, sensitive screening methods are needed. However, during the analytical process of various matrices, such as human serum, some problems appear to regularly occur during sample preparation and storage, leading to MC loss and thus to underestimation of the true MC concentration. The aim of the current study was therefore to assess the pitfalls of the MC-extraction method from human serum with more detail.pi

Fachgebiet (DDC)

540 Chemie

Schlagwörter

ELISA, Microcystin, Human serum, Recovery, Adsorption to lab ware, Hydrophobicity

Zitieren

ISO 690

HEUSSNER, Alexandra H., Stefan ALTANER, Lisa KAMP, Fernando RUBIO, Daniel R. DIETRICH, 2014. Pitfalls in microcystin extraction and recovery from human blood serum. In: Chemico-Biological Interactions. 2014, 223, pp. 87-94. ISSN 0009-2797. eISSN 1872-7786. Available under: doi: 10.1016/j.cbi.2014.08.010

BibTex

@article{Heussner2014Pitfa-29536,
  year={2014},
  doi={10.1016/j.cbi.2014.08.010},
  title={Pitfalls in microcystin extraction and recovery from human blood serum},
  volume={223},
  issn={0009-2797},
  journal={Chemico-Biological Interactions},
  pages={87--94},
  author={Heussner, Alexandra H. and Altaner, Stefan and Kamp, Lisa and Rubio, Fernando and Dietrich, Daniel R.}
}

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