@article{Tkachenko2014unexp-30506,
  year={2014},
  doi={10.3762/bjoc.10.320},
  title={The unexpected influence of aryl substituents in N-aryl-3-oxobutanamides on the behavior of their multicomponent reactions with 5-amino-3-methylisoxazole and salicylaldehyde},
  volume={10},
  journal={Beilstein Journal of Organic Chemistry},
  pages={3019--3030},
  author={Tkachenko, Volodymyr V. and Muravyova, Elena A. and Desenko, Sergey M. and Shishkin, Oleg V. and Shishkina, Svetlana V. and Sysoiev, Dmytro and Müller, Thomas J. J. and Chebanov, Valentin A.}
}

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    <dc:contributor>Müller, Thomas J. J.</dc:contributor>
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    <dc:contributor>Shishkin, Oleg V.</dc:contributor>
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    <dcterms:title>The unexpected influence of aryl substituents in N-aryl-3-oxobutanamides on the behavior of their multicomponent reactions with 5-amino-3-methylisoxazole and salicylaldehyde</dcterms:title>
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    <dcterms:abstract xml:lang="eng">The switchable three-component reactions of 5-amino-3-methylisoxazole, salicylaldehyde and N-aryl-3-oxobutanamides under different conditions were studied and discussed. The unexpected influence of the aryl substituent in N-aryl-3-oxobutanamides on the behavior of the reaction was discovered. The key influence of ultrasonication and Lewis acid catalysts led to an established protocol to selectively obtain two or three types of heterocyclic scaffolds depending on the substituent in the N-aryl moiety.</dcterms:abstract>
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