An NMR Study of Biomimetic Fluorapatite : Gelatine Mesocrystals

Vyalikh, Anastasia; Simon, Paul; Sturm, Elena V.; Buder, Jana; Scheler, Ulrich; Kniep, Ruediger

An NMR Study of Biomimetic Fluorapatite : Gelatine Mesocrystals

Dateien

Vyalikh_0-309134.pdfGröße: 996.25 KBDownloads: 301

Datum

2015

Autor:innen

Vyalikh, Anastasia

Simon, Paul

Sturm, Elena V.

Buder, Jana

Scheler, Ulrich

Kniep, Ruediger

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Chemie
Zukunftskolleg

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Scientific Reports. 2015, 5, 15797. eISSN 2045-2322. Available under: doi: 10.1038/srep15797

Zusammenfassung

The mesocrystal system fluoroapatite-gelatine grown by double-diffusion is characterized by hierarchical composite structure on a mesoscale. In the present work we apply solid state NMR to characterize its structure on the molecular level and provide a link between the structural organisation on the mesoscale and atomistic computer simulations. Thus, we find that the individual nanocrystals are composed of crystalline fluorapatite domains covered by a thin boundary apatite-like layer. The latter is in contact with an amorphous layer, which fills the interparticle space. The amorphous layer is comprised of the organic matrix impregnated by isolated phosphate groups, Ca3F motifs and water molecules. Our NMR data provide clear evidence for the existence of precursor complexes in the gelatine phase, which were not involved in the formation of apatite crystals, proving hence theoretical predictions on the structural pre-treatment of gelatine by ion impregnation. The interfacial interactions, which may be described as the glue holding the composite materials together, comprise hydrogen bond interactions with the apatite PO43- groups. The reported results are in a good agreement with molecular dynamics simulations, which address the mechanisms of a growth control by collagen fibers, and with experimental observations of an amorphous cover layer in biominerals.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

VYALIKH, Anastasia, Paul SIMON, Elena V. STURM, Jana BUDER, Ulrich SCHELER, Ruediger KNIEP, 2015. An NMR Study of Biomimetic Fluorapatite : Gelatine Mesocrystals. In: Scientific Reports. 2015, 5, 15797. eISSN 2045-2322. Available under: doi: 10.1038/srep15797

BibTex

@article{Vyalikh2015Study-33330,
  year={2015},
  doi={10.1038/srep15797},
  title={An NMR Study of Biomimetic Fluorapatite : Gelatine Mesocrystals},
  volume={5},
  journal={Scientific Reports},
  author={Vyalikh, Anastasia and Simon, Paul and Sturm, Elena V. and Buder, Jana and Scheler, Ulrich and Kniep, Ruediger},
  note={Article Number: 15797}
}

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