@article{Stuetz2016Plasm-37538,
  year={2016},
  doi={10.3390/nu8100614},
  title={Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries},
  number={10},
  volume={8},
  journal={Nutrients},
  author={Stuetz, Wolfgang and Weber, Daniela and Dollé, Martijn and Jansen, Eugène and Grubeck-Loebenstein, Beatrix and Fiegl, Simone and Toussaint, Olivier and Bernhardt, Juergen and Moreno-Villanueva, Maria and Bürkle, Alexander},
  note={Article Number: 614}
}

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    <dc:contributor>Fiegl, Simone</dc:contributor>
    <dc:creator>Dollé, Martijn</dc:creator>
    <dc:contributor>Dollé, Martijn</dc:contributor>
    <dc:contributor>Bernhardt, Juergen</dc:contributor>
    <dc:creator>Fiegl, Simone</dc:creator>
    <dc:contributor>Toussaint, Olivier</dc:contributor>
    <dc:contributor>Bürkle, Alexander</dc:contributor>
    <dc:contributor>Stuetz, Wolfgang</dc:contributor>
    <dc:creator>Jansen, Eugène</dc:creator>
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    <dc:contributor>Jansen, Eugène</dc:contributor>
    <dc:language>eng</dc:language>
    <dcterms:title>Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population : A Cross-Sectional Study in Six European Countries</dcterms:title>
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    <dc:contributor>Moreno-Villanueva, Maria</dc:contributor>
    <dcterms:abstract xml:lang="eng">Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels. Significant correlations with age were observed for lycopene (r = -0.248), α-tocopherol (r = 0.208), α-carotene (r = -0.112), and β-cryptoxanthin (r = 0.125; all p &lt; 0.001). Age was inversely associated with lycopene (-6.5% per five-year age increase) and this association remained in the multiple regression model with the significant predictors (covariables) being country, season, cholesterol, gender, smoking status, body mass index (BMI (kg/m²)), and dietary habits. The positive association of α-tocopherol with age remained when all covariates including cholesterol and use of vitamin supplements were included (1.7% vs. 2.4% per five-year age increase). The association of higher β-cryptoxanthin with higher age was no longer statistically significant after adjustment for fruit consumption, whereas the inverse association of α-carotene with age remained in the fully adjusted multivariable model (-4.8% vs. -3.8% per five-year age increase). We conclude from our study that age is an independent predictor of plasma lycopene, α-tocopherol, and α-carotene.</dcterms:abstract>
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    <dc:creator>Stuetz, Wolfgang</dc:creator>
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    <dc:contributor>Weber, Daniela</dc:contributor>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dcterms:issued>2016</dcterms:issued>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dc:creator>Grubeck-Loebenstein, Beatrix</dc:creator>
    <dc:contributor>Grubeck-Loebenstein, Beatrix</dc:contributor>
    <dc:creator>Bürkle, Alexander</dc:creator>
    <dc:creator>Weber, Daniela</dc:creator>
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    <dc:creator>Toussaint, Olivier</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-02-17T08:05:19Z</dc:date>
    <dc:creator>Bernhardt, Juergen</dc:creator>
    <dc:creator>Moreno-Villanueva, Maria</dc:creator>
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