Is the risk of progressive multifocal leukoencephalopathy the real reason for natalizumab discontinuation in patients with multiple sclerosis?

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2017
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Krämer, Julia
Tenberge, Jan-Gerd
Kleiter, Ingo
Ruck, Tobias
Heesen, Christoph
Meuth, Sven G.
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PLOS ONE. 2017, 12(4), e0174858. eISSN 1932-6203. Available under: doi: 10.1371/journal.pone.0174858
Zusammenfassung

Progressive multifocal leukoencephalopathy (PML) is one of the major risks of natalizumab therapy. Despite introduction of the currently employed PML risk stratification algorithm, the incidence of natalizumab-associated PML cases is not decreasing.

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ISO 690KRĂ„MER, Julia, Jan-Gerd TENBERGE, Ingo KLEITER, Wolfgang GAISSMAIER, Tobias RUCK, Christoph HEESEN, Sven G. MEUTH, 2017. Is the risk of progressive multifocal leukoencephalopathy the real reason for natalizumab discontinuation in patients with multiple sclerosis?. In: PLOS ONE. 2017, 12(4), e0174858. eISSN 1932-6203. Available under: doi: 10.1371/journal.pone.0174858
BibTex
@article{Kramer2017progr-39148,
  year={2017},
  doi={10.1371/journal.pone.0174858},
  title={Is the risk of progressive multifocal leukoencephalopathy the real reason for natalizumab discontinuation in patients with multiple sclerosis?},
  number={4},
  volume={12},
  journal={PLOS ONE},
  author={Krämer, Julia and Tenberge, Jan-Gerd and Kleiter, Ingo and Gaissmaier, Wolfgang and Ruck, Tobias and Heesen, Christoph and Meuth, Sven G.},
  note={Article Number: e0174858}
}
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