@article{Mayer2003Chemi-14052,
  year={2003},
  doi={10.1016/S0962-8924(03)00077-1},
  title={Chemical genetics : tailoring tools for cell biology},
  number={5},
  volume={13},
  issn={0962-8924},
  journal={Trends in Cell Biology},
  pages={270--277},
  author={Mayer, Thomas U.}
}

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    <dcterms:bibliographicCitation>Trends Cell Biology ; 13 (2003), 5. - S. 270-277</dcterms:bibliographicCitation>
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    <dcterms:abstract xml:lang="eng">Chemical genetics is a research approach that uses small molecules as probes to study protein functions in cells or whole organisms. Here, I review the parallels between classical genetic and chemical-genetic approaches and discuss the merits of small molecules to dissect dynamic cellular processes. I then consider the pros and cons of different screening approaches and specify strategies aimed at identifying and validating cellular target proteins. Finally, I highlight the impact of chemical genetics on our current understanding of cell biology and its potential for the future.</dcterms:abstract>
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    <dc:contributor>Mayer, Thomas U.</dc:contributor>
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    <dcterms:title>Chemical genetics : tailoring tools for cell biology</dcterms:title>
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