Clinical update on cancer : molecular oncology of head and neck cancer

Suh, Yae-Eun; Amelio, Ivano; Guerrero Urbano, Teresa; Tavassoli, Mahvash

Clinical update on cancer : molecular oncology of head and neck cancer

Dateien

Amelio_2-1jzi3z4hlfp3p1.pdfGröße: 563.83 KBDownloads: 41

Datum

2014

Autor:innen

Suh, Yae-Eun

Amelio, Ivano

Guerrero Urbano, Teresa

Tavassoli, Mahvash

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Cell death & disease. Nature Publishing Group. 2014, 5, e1018. eISSN 2041-4889. Available under: doi: 10.1038/cddis.2013.548

Zusammenfassung

Head and neck cancers encompass a heterogeneous group of tumours that, in general, are biologically aggressive in nature. These cancers remain difficult to treat and treatment can cause severe, long-term side effects. For patients who are not cured by surgery and/or (chemo)radiotherapy, there are few effective treatment options. Targeted therapies and predictive biomarkers are urgently needed in order to improve the management and minimise the treatment toxicity, and to allow selection of patients who are likely to benefit from both nonselective and targeted therapies. This clinical update aims to provide an insight into the current understanding of the molecular pathogenesis of the disease, and explores the novel therapies under development and in clinical trials.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

head and neck squamous cell carcinoma, targeted therapy, HPV, metabolism, hypoxia, biomarkers

Zitieren

ISO 690

SUH, Yae-Eun, Ivano AMELIO, Teresa GUERRERO URBANO, Mahvash TAVASSOLI, 2014. Clinical update on cancer : molecular oncology of head and neck cancer. In: Cell death & disease. Nature Publishing Group. 2014, 5, e1018. eISSN 2041-4889. Available under: doi: 10.1038/cddis.2013.548

BibTex

@article{Suh2014-01-23Clini-57120,
  year={2014},
  doi={10.1038/cddis.2013.548},
  title={Clinical update on cancer : molecular oncology of head and neck cancer},
  volume={5},
  journal={Cell death & disease},
  author={Suh, Yae-Eun and Amelio, Ivano and Guerrero Urbano, Teresa and Tavassoli, Mahvash},
  note={Article Number: e1018}
}

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