Psychological, endocrine, and neural correlates of attentional bias in subclinical depression

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2016
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Dedovic, Katarina
Giebl, Saskia
Duchesne, Annie
Lue, Sonja D.
Andrews, Julie
Efanov, Simona
Engert, Veronika
Beaudry, Thomas
Baldwin, Mark W.
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Anxiety, Stress, & Coping. 2016, 29(5), pp. 479-496. ISSN 1061-5806. eISSN 1477-2205. Available under: doi: 10.1080/10615806.2015.1101457
Zusammenfassung

Background

Our knowledge with respect to psychological, endocrine, and neural correlates of attentional bias in individuals with high vulnerability to developing depression – the subclinically depressed, still remains limited.

Design

The study used a 2 × 2 mixed design.

Methods

Attentional bias toward happy and sad faces in healthy (N = 26) and subclinically depressed individuals (N = 22) was assessed via a neuroimaging dot-probe attention task. Participants also completed trait and state psychological measures and provided saliva samples for cortisol analysis.

Results

The subclinical group showed attentional bias toward happy faces; past use of problem-focused coping strategies when dealing with a personally relevant stressor as well as state levels of anxiety, together, contributed to this bias. In the control group, the happy attentional bias was positively correlated with activity in the right caudate. In the subclinical group, the bias was negatively associated with the left fusiform gyrus and positively with the left inferior parietal lobule and bilateral putamen. We observed group differences in association between cortisol levels during the task and neural activity during happy attentional bias processing within the key regions involved in attention.

Conclusions

The attentional bias toward happy faces may reflect an active coping attempt by the subclinical participants.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
150 Psychologie
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Attentional bias, fMRI, subclinical depression, coping, cortisol
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ISO 690DEDOVIC, Katarina, Saskia GIEBL, Annie DUCHESNE, Sonja D. LUE, Julie ANDREWS, Simona EFANOV, Veronika ENGERT, Thomas BEAUDRY, Mark W. BALDWIN, Jens C. PRUESSNER, 2016. Psychological, endocrine, and neural correlates of attentional bias in subclinical depression. In: Anxiety, Stress, & Coping. 2016, 29(5), pp. 479-496. ISSN 1061-5806. eISSN 1477-2205. Available under: doi: 10.1080/10615806.2015.1101457
BibTex
@article{Dedovic2016-09-02Psych-38160,
  year={2016},
  doi={10.1080/10615806.2015.1101457},
  title={Psychological, endocrine, and neural correlates of attentional bias in subclinical depression},
  number={5},
  volume={29},
  issn={1061-5806},
  journal={Anxiety, Stress, & Coping},
  pages={479--496},
  author={Dedovic, Katarina and Giebl, Saskia and Duchesne, Annie and Lue, Sonja D. and Andrews, Julie and Efanov, Simona and Engert, Veronika and Beaudry, Thomas and Baldwin, Mark W. and Pruessner, Jens C.}
}
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