@article{Xu2022-07-22Genom-58466,
  year={2022},
  doi={10.3389/fgene.2022.906447},
  title={Genomic Analyses for Selective Signatures and Genes Involved in Hot Adaptation Among Indigenous Chickens From Different Tropical Climate Regions},
  volume={13},
  journal={Frontiers in Genetics},
  author={Xu, Nai-Yi and Liu, Zhen-Yu and Yang, Qi-Meng and Bian, Pei-Pei and Li, Ming and Zhao, Xin},
  note={Article Number: 906447}
}

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    <dc:contributor>Bian, Pei-Pei</dc:contributor>
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    <dc:creator>Xu, Nai-Yi</dc:creator>
    <dc:creator>Liu, Zhen-Yu</dc:creator>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dc:contributor>Zhao, Xin</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-09-01T09:06:00Z</dc:date>
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    <dcterms:abstract xml:lang="eng">Climate change, especially weather extremes like extreme cold or extreme hot, is a major challenge for global livestock. One of the animal breeding goals for sustainable livestock production should be to breed animals with excellent climate adaptability. Indigenous livestock and poultry are well adapted to the local climate, and they are good resources to study the genetic footprints and mechanism of the resilience to weather extremes. In order to identify selection signatures and genes that might be involved in hot adaptation in indigenous chickens from different tropical climates, we conducted a genomic analysis of 65 indigenous chickens that inhabit different climates. Several important unique positively selected genes (PSGs) were identified for each local chicken group by the cross-population extended haplotype homozygosity (XP-EHH). These PSGs, verified by composite likelihood ratio, genetic differentiation index, nucleotide diversity, Tajima’s D, and decorrelated composite of multiple signals, are related to nerve regulation, vascular function, immune function, lipid metabolism, kidney development, and function, which are involved in thermoregulation and hot adaptation. However, one common PSG was detected for all three tropical groups of chickens via XP-EHH but was not confirmed by other five types of selective sweep analyses. These results suggest that the hot adaptability of indigenous chickens from different tropical climate regions has evolved in parallel by taking different pathways with different sets of genes. The results from our study have provided reasonable explanations and insights for the rapid adaptation of chickens to diverse tropical climates and provide practical values for poultry breeding.</dcterms:abstract>
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    <dcterms:title>Genomic Analyses for Selective Signatures and Genes Involved in Hot Adaptation Among Indigenous Chickens From Different Tropical Climate Regions</dcterms:title>
    <dc:creator>Zhao, Xin</dc:creator>
    <dc:creator>Li, Ming</dc:creator>
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    <dc:creator>Yang, Qi-Meng</dc:creator>
    <dc:contributor>Liu, Zhen-Yu</dc:contributor>
    <dc:contributor>Li, Ming</dc:contributor>
    <dc:contributor>Yang, Qi-Meng</dc:contributor>
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