Nodal and BMP dispersal during early zebrafish development

Rogers, Katherine W.; Müller, Patrick

Nodal and BMP dispersal during early zebrafish development

Dateien

Rogers_2-2zyglpt8nokk4.pdfGröße: 1.47 MBDownloads: 11

Datum

2019

Autor:innen

Rogers, Katherine W.

Müller, Patrick

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002

Zusammenfassung

The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation, and BMP specifies ventral fates and patterns the dorsal/ventral axis. Five major models have been proposed to explain how the correct distributions of Nodal and BMP are achieved within tissues to orchestrate embryogenesis: source/sink, transcriptional determination, relay, self-regulation, and shuttling. Here, we discuss recent experiments probing these signal dispersal models, focusing on early zebrafish development.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

ROGERS, Katherine W., Patrick MÜLLER, 2019. Nodal and BMP dispersal during early zebrafish development. In: Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002

BibTex

@article{Rogers2019Nodal-55565,
  year={2019},
  doi={10.1016/j.ydbio.2018.04.002},
  title={Nodal and BMP dispersal during early zebrafish development},
  number={1},
  volume={447},
  issn={0012-1606},
  journal={Developmental Biology},
  pages={14--23},
  author={Rogers, Katherine W. and Müller, Patrick}
}

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