Spatially resolved transcriptomics in immersive environments

Lade...
Vorschaubild
Dateien
Bienroth_2-r2sstvqpa09y7.pdf
Bienroth_2-r2sstvqpa09y7.pdfGröße: 3.58 MBDownloads: 148
Datum
2022
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Hybrid
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Visual computing for industry, biomedicine, and art. Springer. 2022, 5(1), 2. eISSN 2524-4442. Available under: doi: 10.1186/s42492-021-00098-6
Zusammenfassung

Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, VR-Cardiomics is presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
004 Informatik
Schlagwörter
Spatially-resolved transcriptomics, Spatial transcriptomics, Virtual reality, Fish tank virtual reality, Head-mounted display, Immersive analytics, Immersive environment
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690BIENROTH, Denis, Hieu T. NIM, Dimitar GARKOV, Karsten KLEIN, Sabrina JAEGER, Mirana RAMIALISON, Falk SCHREIBER, 2022. Spatially resolved transcriptomics in immersive environments. In: Visual computing for industry, biomedicine, and art. Springer. 2022, 5(1), 2. eISSN 2524-4442. Available under: doi: 10.1186/s42492-021-00098-6
BibTex
@article{Bienroth2022-01-10Spati-56138,
  year={2022},
  doi={10.1186/s42492-021-00098-6},
  title={Spatially resolved transcriptomics in immersive environments},
  number={1},
  volume={5},
  journal={Visual computing for industry, biomedicine, and art},
  author={Bienroth, Denis and Nim, Hieu T. and Garkov, Dimitar and Klein, Karsten and Jaeger, Sabrina and Ramialison, Mirana and Schreiber, Falk},
  note={Article Number: 2}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/56138">
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56138/1/Bienroth_2-r2sstvqpa09y7.pdf"/>
    <dcterms:abstract xml:lang="eng">Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, VR-Cardiomics is presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.</dcterms:abstract>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dcterms:issued>2022-01-10</dcterms:issued>
    <dc:creator>Schreiber, Falk</dc:creator>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dc:creator>Garkov, Dimitar</dc:creator>
    <dc:contributor>Jaeger, Sabrina</dc:contributor>
    <dc:creator>Bienroth, Denis</dc:creator>
    <dc:language>eng</dc:language>
    <dc:creator>Nim, Hieu T.</dc:creator>
    <dc:contributor>Nim, Hieu T.</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56138/1/Bienroth_2-r2sstvqpa09y7.pdf"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/36"/>
    <dc:contributor>Klein, Karsten</dc:contributor>
    <dc:contributor>Ramialison, Mirana</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Ramialison, Mirana</dc:creator>
    <dc:contributor>Garkov, Dimitar</dc:contributor>
    <dc:creator>Klein, Karsten</dc:creator>
    <dcterms:title>Spatially resolved transcriptomics in immersive environments</dcterms:title>
    <dc:contributor>Bienroth, Denis</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/56138"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/36"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-01-17T09:07:20Z</dc:date>
    <dc:creator>Jaeger, Sabrina</dc:creator>
    <dc:contributor>Schreiber, Falk</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-01-17T09:07:20Z</dcterms:available>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen