@article{Alder2012-03-16carot-23568,
  year={2012},
  doi={10.1126/science.1218094},
  title={The path from β-carotene to carlactone, a strigolactone-like plant hormone},
  number={6074},
  volume={335},
  issn={0036-8075},
  journal={Science},
  pages={1348--1351},
  author={Alder, Adrian and Jamil, Muhammad and Marzorati, Mattia and Bruno, Mark and Vermathen, Martina and Bigler, Peter and Ghisla, Sandro and Bouwmeester, Harro and Beyer, Peter and Al-Babili, Salim}
}

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    <dc:contributor>Ghisla, Sandro</dc:contributor>
    <dcterms:issued>2012-03-16</dcterms:issued>
    <dc:contributor>Bigler, Peter</dc:contributor>
    <dc:contributor>Alder, Adrian</dc:contributor>
    <dc:creator>Bigler, Peter</dc:creator>
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    <dc:contributor>Bruno, Mark</dc:contributor>
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    <dc:creator>Al-Babili, Salim</dc:creator>
    <dc:creator>Ghisla, Sandro</dc:creator>
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    <dcterms:title>The path from β-carotene to carlactone, a strigolactone-like plant hormone</dcterms:title>
    <dcterms:abstract xml:lang="eng">Strigolactones, phytohormones with diverse signaling activities, have a common structure consisting of two lactones connected by an enol-ether bridge. Strigolactones derive from carotenoids via a pathway involving the carotenoid cleavage dioxygenases 7 and 8 (CCD7 and CCD8) and the iron-binding protein D27. We show that D27 is a β-carotene isomerase that converts all-trans-β-carotene into 9-cis-β-carotene, which is cleaved by CCD7 into a 9-cis–configured aldehyde. CCD8 incorporates three oxygens into 9-cis-β-apo-10'-carotenal and performs molecular rearrangement, linking carotenoids with strigolactones and producing carlactone, a compound with strigolactone-like biological activities. Knowledge of the structure of carlactone will be crucial for understanding the biology of strigolactones and may have applications in combating parasitic weeds.</dcterms:abstract>
    <dc:contributor>Al-Babili, Salim</dc:contributor>
    <dc:contributor>Beyer, Peter</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-06-11T14:26:34Z</dc:date>
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    <dc:creator>Bruno, Mark</dc:creator>
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    <dc:creator>Jamil, Muhammad</dc:creator>
    <dc:creator>Beyer, Peter</dc:creator>
    <dc:contributor>Vermathen, Martina</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dc:creator>Alder, Adrian</dc:creator>
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    <dc:contributor>Jamil, Muhammad</dc:contributor>
    <dcterms:bibliographicCitation>Science ; 335 (2012), 6074. - S. 1348-1351</dcterms:bibliographicCitation>
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