Evidence for the 'Good Genes' Model : Association of MHC Class II DRB Alleles with Ectoparasitism and Reproductive State in the Neotropical Lesser Bulldog Bat, Noctilio albiventris
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The adaptive immune system has a major impact on parasite resistance and life history strategies. Immunological defence is costly both in terms of immediate activation and long-term maintenance. The ‘good genes’ model predicts that males with genotypes that promote a good disease resistance have the ability to allocate more resources to reproductive effort which favours the transmission of good alleles into future generations. Our study shows a correlation between immune gene constitution (Major Histocompatibility Complex, MHC class II DRB), ectoparasite loads (ticks and bat flies) and the reproductive state in a neotropical bat, Noctilio albiventris. Infestation rates with ectoparasites were linked to specific Noal-DRB alleles, differed among roosts, increased with body size and co-varied with reproductive state particularly in males. Non-reproductive adult males were more infested with ectoparasites than reproductively active males, and they had more often an allele (Noal-DRB*02) associated with a higher tick infestation than reproductively active males or subadults. We conclude that the individual immune gene constitution affects ectoparasite susceptibility, and contributes to fitness relevant trade-offs in male N. albiventris as suggested by the 'good genes' model.
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SCHAD, Julia, Dina K. N. DECHMANN, Christian C. VOIGT, Simone SOMMER, 2012. Evidence for the 'Good Genes' Model : Association of MHC Class II DRB Alleles with Ectoparasitism and Reproductive State in the Neotropical Lesser Bulldog Bat, Noctilio albiventris. In: PLoS ONE. 2012, 7(5), e37101. eISSN 1932-6203. Available under: doi: 10.1371/journal.pone.0037101BibTex
@article{Schad2012Evide-23685, year={2012}, doi={10.1371/journal.pone.0037101}, title={Evidence for the 'Good Genes' Model : Association of MHC Class II DRB Alleles with Ectoparasitism and Reproductive State in the Neotropical Lesser Bulldog Bat, Noctilio albiventris}, number={5}, volume={7}, journal={PLoS ONE}, author={Schad, Julia and Dechmann, Dina K. N. and Voigt, Christian C. and Sommer, Simone}, note={Article Number: e37101} }
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