Dual control by a single gene of secondary sexual characters and mating preferences in medaka

Fukamachi, Shoji; Kinoshita, Masato; Aizawa, Kouichi; Oda, Shoji; Meyer, Axel; Mitani, Hiroshi

Dual control by a single gene of secondary sexual characters and mating preferences in medaka

Dateien

Fukamachi_105095.pdfGröße: 929.57 KBDownloads: 186

Datum

2009

Autor:innen

Fukamachi, Shoji

Kinoshita, Masato

Aizawa, Kouichi

Oda, Shoji

Meyer, Axel

Mitani, Hiroshi

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

BMC Biology. 2009, 7(1), 64. eISSN 1741-7007. Available under: doi: 10.1186/1741-7007-7-64

Zusammenfassung

Background:
Animals utilize a wide variety of tactics to attract reproductive partners. Behavioral experiments often indicate an important role for visual cues in fish, but their molecular basis remains almost entirely unknown. Studies on model species (such as zebrafish and medaka) allow investigations into this fundamental question in behavioral and evolutionary biology.
Results:
Through mate-choice experiences using several laboratory strains of various body colors, we successfully identified one medaka mutant (color interfere; ci) that is distinctly unattractive to reproductive partners. This unattractiveness seems to be due to reduced orange pigment cells (xanthophores) in the skin. The ci strain carries a mutation on the somatolactin alpha (SLa) gene, therefore we expected over-expression of SLa to make medaka hyper-attractive. Indeed, extremely strong mating preferences were detected in a choice between the ci and SLa-transgenic (Actb-SLa:GFP) medaka. Intriguingly, however, the strains showed opposite biases; that is, the mutant and transgenic medaka liked to mate with partners from their own strain, similar to becoming sexually isolated.
Conclusion:
This study spotlighted SLa as a novel mate-choice gene in fish. In addition, these results are the first demonstration of a single gene that can pleiotropically and harmoniously change both secondary sexual characters and mating preferences. Although theoretical models have long suggested joint evolution of linked genes on a chromosome, a mutation on a gene-regulatory region (that is, switching on/off of a single gene) might be sufficient to trigger two 'runaway' processes in different directions to promote (sympatric) speciation.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

FUKAMACHI, Shoji, Masato KINOSHITA, Kouichi AIZAWA, Shoji ODA, Axel MEYER, Hiroshi MITANI, 2009. Dual control by a single gene of secondary sexual characters and mating preferences in medaka. In: BMC Biology. 2009, 7(1), 64. eISSN 1741-7007. Available under: doi: 10.1186/1741-7007-7-64

BibTex

@article{Fukamachi2009contr-6665,
  year={2009},
  doi={10.1186/1741-7007-7-64},
  title={Dual control by a single gene of secondary sexual characters and mating preferences in medaka},
  number={1},
  volume={7},
  journal={BMC Biology},
  author={Fukamachi, Shoji and Kinoshita, Masato and Aizawa, Kouichi and Oda, Shoji and Meyer, Axel and Mitani, Hiroshi},
  note={Article Number: 64}
}

RDF

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/6665">
    <dc:creator>Meyer, Axel</dc:creator>
    <dc:contributor>Aizawa, Kouichi</dc:contributor>
    <dc:contributor>Mitani, Hiroshi</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Oda, Shoji</dc:contributor>
    <dc:creator>Oda, Shoji</dc:creator>
    <dc:format>application/pdf</dc:format>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6665"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6665/1/Fukamachi_105095.pdf"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:11Z</dc:date>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6665/1/Fukamachi_105095.pdf"/>
    <dc:creator>Aizawa, Kouichi</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:11Z</dcterms:available>
    <dc:contributor>Meyer, Axel</dc:contributor>
    <dc:creator>Fukamachi, Shoji</dc:creator>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/2.0/"/>
    <dcterms:abstract xml:lang="eng">Background:&lt;br /&gt;Animals utilize a wide variety of tactics to attract reproductive partners. Behavioral experiments often indicate an important role for visual cues in fish, but their molecular basis remains almost entirely unknown. Studies on model species (such as zebrafish and medaka) allow investigations into this fundamental question in behavioral and evolutionary biology.&lt;br /&gt;Results:&lt;br /&gt;Through mate-choice experiences using several laboratory strains of various body colors, we successfully identified one medaka mutant (color interfere; ci) that is distinctly unattractive to reproductive partners. This unattractiveness seems to be due to reduced orange pigment cells (xanthophores) in the skin. The ci strain carries a mutation on the somatolactin alpha (SLa) gene, therefore we expected over-expression of SLa to make medaka hyper-attractive. Indeed, extremely strong mating preferences were detected in a choice between the ci and SLa-transgenic (Actb-SLa:GFP) medaka. Intriguingly, however, the strains showed opposite biases; that is, the mutant and transgenic medaka liked to mate with partners from their own strain, similar to becoming sexually isolated.&lt;br /&gt;Conclusion:&lt;br /&gt;This study spotlighted SLa as a novel mate-choice gene in fish. In addition, these results are the first demonstration of a single gene that can pleiotropically and harmoniously change both secondary sexual characters and mating preferences. Although theoretical models have long suggested joint evolution of linked genes on a chromosome, a mutation on a gene-regulatory region (that is, switching on/off of a single gene) might be sufficient to trigger two 'runaway' processes in different directions to promote (sympatric) speciation.</dcterms:abstract>
    <dcterms:bibliographicCitation>First publ. in: BMC Biology ; 7 (2009). - 64</dcterms:bibliographicCitation>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:issued>2009</dcterms:issued>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Kinoshita, Masato</dc:creator>
    <dc:rights>Attribution 2.0 Generic</dc:rights>
    <dc:contributor>Kinoshita, Masato</dc:contributor>
    <dc:contributor>Fukamachi, Shoji</dc:contributor>
    <dc:creator>Mitani, Hiroshi</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:title>Dual control by a single gene of secondary sexual characters and mating preferences in medaka</dcterms:title>
  </rdf:Description>
</rdf:RDF>

Universitätsbibliographie

Ja