@article{SaintRuf2009Analy-1252,
  year={2009},
  title={Analysis and expression of a cloned pre-T cell receptor gene},
  number={9},
  volume={182},
  journal={The Journal of Immunology},
  pages={5165--5169},
  author={Saint-Ruf, Claude and Ungewiss, Katharina and Gröttrup, Marcus and Bruno, Ludovica and Fehling, Hans Jörg and Boehmer, Harald von}
}

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    <dc:creator>Boehmer, Harald von</dc:creator>
    <dc:creator>Saint-Ruf, Claude</dc:creator>
    <dc:language>eng</dc:language>
    <dc:contributor>Boehmer, Harald von</dc:contributor>
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    <dcterms:bibliographicCitation>Publ. in: The Journal of Immunology 182 (2009), 9, pp. 5165-5169</dcterms:bibliographicCitation>
    <dc:creator>Fehling, Hans Jörg</dc:creator>
    <dcterms:abstract xml:lang="eng">The T cell antigen receptor (TCR) p chain regulates early T cell development in the absence of the TCRa chain. The developmentally controlled gene described here encodes the pre-TCRa (pTa) chain, which covalently associates with TCRp and with the CD3 proteins forms a pre-TCR complex that transduces signals in immature thymocytes. Unlike the λ5 pre-B cell receptor protein, the pTa chain is a type I transmembrane protein whose cytoplasmic tail contains two potential phosphorylation sites and a Src homology 3 (SH3)-domain binding sequence. Pre-TCRa transfection experiments indicated that surface expression of the pre-TCR is controlled by additional developmentally regulated proteins. Identification of the pTa gene represents an essential step in the structure-function analysis of the pre-TCR complex.</dcterms:abstract>
    <dc:creator>Bruno, Ludovica</dc:creator>
    <dc:rights>terms-of-use</dc:rights>
    <dc:contributor>Gröttrup, Marcus</dc:contributor>
    <dcterms:title>Analysis and expression of a cloned pre-T cell receptor gene</dcterms:title>
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    <dc:creator>Ungewiss, Katharina</dc:creator>
    <dc:contributor>Fehling, Hans Jörg</dc:contributor>
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    <dc:contributor>Ungewiss, Katharina</dc:contributor>
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    <dc:creator>Gröttrup, Marcus</dc:creator>
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    <dc:contributor>Saint-Ruf, Claude</dc:contributor>
    <dc:contributor>Bruno, Ludovica</dc:contributor>
    <dcterms:issued>2009</dcterms:issued>
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