@article{Langhorst2007-10-02Linki-1146,
  year={2007},
  doi={10.1016/j.febslet.2007.08.066},
  title={Linking membrane microdomains to the cytoskeleton : regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin},
  number={24},
  volume={581},
  issn={0014-5793},
  journal={FEBS Letters},
  pages={4704--4710},
  author={Langhorst, Matthias F. and Solis Padilla, Gonzalo and Hannbeck, Sylvia and Plattner, Helmut and Stürmer, Claudia}
}

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/1146">
    <dc:creator>Langhorst, Matthias F.</dc:creator>
    <dc:contributor>Plattner, Helmut</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-23T09:06:27Z</dc:date>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Stürmer, Claudia</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-23T09:06:27Z</dcterms:available>
    <dc:creator>Plattner, Helmut</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Stürmer, Claudia</dc:creator>
    <dcterms:bibliographicCitation>Publ. in: FEBS Letters ; 581 (2007), 24. - S. 4697-4703</dcterms:bibliographicCitation>
    <dc:contributor>Langhorst, Matthias F.</dc:contributor>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/1146"/>
    <dc:contributor>Solis Padilla, Gonzalo</dc:contributor>
    <dcterms:issued>2007-10-02</dcterms:issued>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Solis Padilla, Gonzalo</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/1146/1/Plattneretal.pdf"/>
    <dcterms:abstract xml:lang="eng">The reggies/flotillins are oligomeric scaffolding proteins for membrane microdomains. We show here that reggie-1/flotillin-2 microdomains are organized along cortical F-actin in several cell types. Interaction with F-actin is mediated by the SPFH domain as shown by in vivo co-localization and in vitro binding experiments. Reggie-1/flotillin-2 microdomains form independent of actin, but disruption or stabilization of the actin cytoskeleton modulate the lateral mobility of reggie-1/flotillin-2 as shown by FRAP. Furthermore, reggie/flotillin microdomains can efficiently be immobilized by actin polymerisation, while exchange of reggie-1/flotillin-2 molecules between microdomains is enhanced by actin disruption as shown by tracking of individual microdomains using TIRF microscopy.</dcterms:abstract>
    <dc:creator>Hannbeck, Sylvia</dc:creator>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/1146/1/Plattneretal.pdf"/>
    <dc:contributor>Hannbeck, Sylvia</dc:contributor>
    <dcterms:title>Linking membrane microdomains to the cytoskeleton : regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin</dcterms:title>
  </rdf:Description>
</rdf:RDF>