Phylogenetic Performance of Mitochondrial Protein-Coding Genes in Resolving Relationships Among Vertebrates

Zardoya, Rafael; Meyer, Axel

Phylogenetic Performance of Mitochondrial Protein-Coding Genes in Resolving Relationships Among Vertebrates

Dateien

Phylogenetic_Performance_of_Mitochondrial_Protein_Coding_1996.pdfGröße: 290.97 KBDownloads: 565

Datum

1996

Autor:innen

Zardoya, Rafael

Meyer, Axel

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Molecular Biology and Evolution. 1996, 13(7), pp. 933-942. ISSN 0737-4038. eISSN 1537-1719. Available under: doi: 10.1093/oxfordjournals.molbev.a025661

Zusammenfassung

A large number of studies in evolutionary biology utilize phylogenetic information obtained from mitochondrial DNA. Researchers place trust in this molecule and expect it generally to be a reliable marker for addressing questions ranging from population genetics to phylogenies among distantly related lineages. Yet, regardless of the phylogenetic method and weighting treatment, individual mitochondrial genes might potentially produce misleading evolutionary inferences and hence might not constitute an adequate representation neither of the entire mitochondrial genome nor of the evolutionary history of the organisms from which they are derived. We investigated the performance of all mitochondrial protein-coding genes to recover two expected phylogenies of tetrapods and mammals. According to these tests, mitochondrial protein-coding genes can be roughly classified into three groups of good (ND4, ND5, ND2, cytb, and COI), medium (COB, COIII, NDl, and ND6), and poor (ATPase 6, ND3, ATPase 8, and ND4L) phylogenetic performers in recovering these expected trees among phylogenetically distant relatives. How general our findings are is unclear. Simple length differences and rate differences between these genes cannot account for their different phylogenetic performance. The phylogenetic performance of these mitochondrial genes might depend on various factors that play a role in determining the probability of discovering the correct phylogeny such as the density of lineage creation events in time, the phylogenetic depth of the question, lineage-specific rate heterogeneity, and the completeness of taxa representation.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

mtDNA, vertebrate phylogeny, maximum likelihood, maximum parsimony, protein-coding genes

Zitieren

ISO 690

ZARDOYA, Rafael, Axel MEYER, 1996. Phylogenetic Performance of Mitochondrial Protein-Coding Genes in Resolving Relationships Among Vertebrates. In: Molecular Biology and Evolution. 1996, 13(7), pp. 933-942. ISSN 0737-4038. eISSN 1537-1719. Available under: doi: 10.1093/oxfordjournals.molbev.a025661

BibTex

@article{Zardoya1996Phylo-8447,
  year={1996},
  doi={10.1093/oxfordjournals.molbev.a025661},
  title={Phylogenetic Performance of Mitochondrial Protein-Coding Genes in Resolving Relationships Among Vertebrates},
  number={7},
  volume={13},
  issn={0737-4038},
  journal={Molecular Biology and Evolution},
  pages={933--942},
  author={Zardoya, Rafael and Meyer, Axel}
}

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Universitätsbibliographie

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