Structure of the Rotor Ring of F-Type NA+-ATPase from Ilyobacter tartaricus

Meier, Thomas; Polzer, Patrick; Diederichs, Kay; Welte, Wolfram; Dimroth, Peter

Structure of the Rotor Ring of F-Type NA+-ATPase from Ilyobacter tartaricus

Dateien

71_science_308_659.pdfGröße: 427.68 KBDownloads: 803

Datum

2005

Autor:innen

Meier, Thomas

Polzer, Patrick

Diederichs, Kay

Welte, Wolfram

Dimroth, Peter

URI (zitierfähiger Link)

http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-40063

Link zur Lizenz

Attribution-NonCommercial-NoDerivs 2.0 Generic

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Science. 2005, 308(5722), pp. 659-662. ISSN 0036-8075. eISSN 1095-9203

Zusammenfassung

In the crystal structure of the membrane-embedded rotor ring of the sodium ion translocating adenosine 5¶-triphosphate (ATP) synthase of Ilyobacter tartaricus at 2.4 angstrom resolution, 11 c subunits are assembled into an hourglass-shaped cylinder with 11-fold symmetry. Sodium ions are bound in a locked conformation close to the outer surface of the cylinder near the middle of the membrane. The structure supports an ion-translocation mechanism in the intact ATP synthase in which the binding site converts from the locked conformation into one that opens toward subunit a as the rotor ring moves through the subunit a/c interface.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

MEIER, Thomas, Patrick POLZER, Kay DIEDERICHS, Wolfram WELTE, Peter DIMROTH, 2005. Structure of the Rotor Ring of F-Type NA+-ATPase from Ilyobacter tartaricus. In: Science. 2005, 308(5722), pp. 659-662. ISSN 0036-8075. eISSN 1095-9203

BibTex

@article{Meier2005Struc-6683,
  year={2005},
  title={Structure of the Rotor Ring of F-Type NA+-ATPase from Ilyobacter tartaricus},
  number={5722},
  volume={308},
  issn={0036-8075},
  journal={Science},
  pages={659--662},
  author={Meier, Thomas and Polzer, Patrick and Diederichs, Kay and Welte, Wolfram and Dimroth, Peter}
}

RDF

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/6683">
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:bibliographicCitation>First publ. in: Science Magazine 308 (2005), pp. 659-662</dcterms:bibliographicCitation>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6683/1/71_science_308_659.pdf"/>
    <dc:creator>Meier, Thomas</dc:creator>
    <dc:creator>Welte, Wolfram</dc:creator>
    <dcterms:issued>2005</dcterms:issued>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:20Z</dcterms:available>
    <dc:format>application/pdf</dc:format>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Diederichs, Kay</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6683/1/71_science_308_659.pdf"/>
    <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
    <dc:creator>Dimroth, Peter</dc:creator>
    <dc:contributor>Welte, Wolfram</dc:contributor>
    <dc:contributor>Diederichs, Kay</dc:contributor>
    <dc:creator>Polzer, Patrick</dc:creator>
    <dcterms:abstract xml:lang="eng">In the crystal structure of the membrane-embedded rotor ring of the sodium ion translocating adenosine 5¶-triphosphate (ATP) synthase of Ilyobacter tartaricus at 2.4 angstrom resolution, 11 c subunits are assembled into an hourglass-shaped cylinder with 11-fold symmetry. Sodium ions are bound in a locked conformation close to the outer surface of the cylinder near the middle of the membrane. The structure supports an ion-translocation mechanism in the intact ATP synthase in which the binding site converts from the locked conformation into one that opens toward subunit a as the rotor ring moves through the subunit a/c interface.</dcterms:abstract>
    <dc:contributor>Dimroth, Peter</dc:contributor>
    <dc:language>eng</dc:language>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6683"/>
    <dcterms:title>Structure of the Rotor Ring of F-Type NA+-ATPase from Ilyobacter tartaricus</dcterms:title>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:28:20Z</dc:date>
    <dc:contributor>Polzer, Patrick</dc:contributor>
    <dc:contributor>Meier, Thomas</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
  </rdf:Description>
</rdf:RDF>

Universitätsbibliographie

Ja