Cellular adhesion molecules as targets for bacterial infection

Hauck, Christof R.; Agerer, Franziska; Münzner, Petra; Schmitter, Tim

Cellular adhesion molecules as targets for bacterial infection

Dateien

2006_Hauck_et_al_EurJCellBiol.pdfGröße: 468.71 KBDownloads: 709

Datum

2006

Autor:innen

Hauck, Christof R.

Agerer, Franziska

Münzner, Petra

Schmitter, Tim

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

European Journal of Cell Biology. 2006, 85(3/4), pp. 235-242. ISSN 0171-9335. Available under: doi: 10.1016/j.ejcb.2005.08.002

Zusammenfassung

A large number of bacterial pathogens targets cell adhesion molecules to establish an intimate contact with host cells and tissues. Members of the integrin, cadherin and immunoglobulin-related cell adhesion molecule (IgCAM) families are frequently recognized by specific bacterial surface proteins. Binding can trigger bacterial internalization following cytoskeletal rearrangements that are initiated upon receptor clustering. Moreover, signals emanating from the occupied receptors can result in cellular responses such as gene expression events that influence the phenotype of the infected cell. This review will address recent advances in our understanding of bacterial engagement of cellular adhesion molecules by discussing the binding of integrins by Staphylococcus aureus as well as the exploitation of IgCAMs by pathogenic Neisseria species.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

Neisseria gonorrhoeae, Staphylococcus aureus, Bacterial invasion, Cell adhesion, Integrin, CEACAM

Zitieren

ISO 690

HAUCK, Christof R., Franziska AGERER, Petra MÜNZNER, Tim SCHMITTER, 2006. Cellular adhesion molecules as targets for bacterial infection. In: European Journal of Cell Biology. 2006, 85(3/4), pp. 235-242. ISSN 0171-9335. Available under: doi: 10.1016/j.ejcb.2005.08.002

BibTex

@article{Hauck2006Cellu-6536,
  year={2006},
  doi={10.1016/j.ejcb.2005.08.002},
  title={Cellular adhesion molecules as targets for bacterial infection},
  number={3/4},
  volume={85},
  issn={0171-9335},
  journal={European Journal of Cell Biology},
  pages={235--242},
  author={Hauck, Christof R. and Agerer, Franziska and Münzner, Petra and Schmitter, Tim}
}

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Universitätsbibliographie

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