Recovery from aphasia as a function of language therapy in an early bilingual patient demonstrated by fMRI

Meinzer, Marcus; Obleser, Jonas; Flaisch, Tobias; Eulitz, Carsten; Rockstroh, Brigitte

Recovery from aphasia as a function of language therapy in an early bilingual patient demonstrated by fMRI

Dateien

recovery_from_aphasia_as_a_function_of_language_therapy.pdfGröße: 739.79 KBDownloads: 1298

Datum

2007

Autor:innen

Meinzer, Marcus

Obleser, Jonas

Flaisch, Tobias

Eulitz, Carsten

Rockstroh, Brigitte

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Psychologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Neuropsychologia. 2007, 45(6), pp. 1247-1256. Available under: doi: 10.1016/j.neuropsychologia.2006.10.003

Zusammenfassung

Knowledge about the recovery of language functions in bilingual aphasic patients who suffer from left-hemispheric stroke is scarce. Here, we present the case of an early bilingual patient (German/French) with chronic aphasia. Functional magnetic resonance imaging (fMRI) was used to investigate neural correlates of language performance during an overt picture naming task in German and French (a) 32 months after stroke to assess differential recovery of both languages as a function of the preceding language therapy that was provided exclusively in German and (b) after additional short-term intensive (German) language training. At the first investigation behavioral performance confirmed selective recovery of German naming ability which was associated with increased functional brain activation compared to the French naming condition. Changes in behavioral performance and brain activation pattern as disclosed by fMRI after an additional experimental treatment were confined to the trained (German) language and indicate bilateral neuroplastic reorganization. No generalization to the untrained (French) language was observed. The present case results demonstrate use and/or training-dependent differential recovery of expressive language functions and an enhanced pattern of brain activation as a function of the rehabilitation efforts that were focussed exclusively on the patient's German language abilities.

Fachgebiet (DDC)

150 Psychologie

Schlagwörter

language disorder, stroke, bilingualism, treatment, functional imaging

Zitieren

ISO 690

MEINZER, Marcus, Jonas OBLESER, Tobias FLAISCH, Carsten EULITZ, Brigitte ROCKSTROH, 2007. Recovery from aphasia as a function of language therapy in an early bilingual patient demonstrated by fMRI. In: Neuropsychologia. 2007, 45(6), pp. 1247-1256. Available under: doi: 10.1016/j.neuropsychologia.2006.10.003

BibTex

@article{Meinzer2007Recov-11028,
  year={2007},
  doi={10.1016/j.neuropsychologia.2006.10.003},
  title={Recovery from aphasia as a function of language therapy in an early bilingual patient demonstrated by fMRI},
  number={6},
  volume={45},
  journal={Neuropsychologia},
  pages={1247--1256},
  author={Meinzer, Marcus and Obleser, Jonas and Flaisch, Tobias and Eulitz, Carsten and Rockstroh, Brigitte}
}

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Universitätsbibliographie

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