Effect of Task Conditions on Brain Responses to Threatening Faces in Social Phobics : An Event-Related Functional Magnetic Resonance Imaging Study

Lade...
Vorschaubild
Datum
2004
Autor:innen
Straube, Thomas
Glauer, Madlen
Mentzel, Hans-Joachim
Miltner, Wolfgang H. R.
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Biological Psychiatry. 2004, 56, pp. 921-930. Available under: doi: 10.1016/j.biopsych.2004.09.024
Zusammenfassung

Background: The aim of this study was to identify brain activation to socially threatening stimuli in social phobic subjects during different experimental conditions.
Methods: With event-related functional magnetic resonance imaging, brain activation to photographs and schematic pictures depicting angry or neutral facial expressions was measured in social phobic subjects and healthy control subjects, while subjects assessed either emotional expression (angry vs. neutral; explicit task) or picture type (photographic vs. schematic; implicit task).
Results: Compared with control subjects, phobics showed greater responses to angry than to neutral photographic faces in the insula regardless of task, whereas amygdala, parahippocampal gyrus, and extrastriate visual cortex were more strongly activated only during the implicit task. Phobics, in contrast to control subjects, showed similar activation patterns during both tasks. For schematic angry versus neutral faces, activation of insula and extrastriate visual cortex was found in phobics, but not in control subjects, during both tasks.
Conclusions: Differences between social phobics and control subjects in brain responses to socially threatening faces are most pronounced when facial expression is task-irrelevant. Phobics intensively process angry (photographic as well as schematic) facial expressions, regardless of whether this is required. The insula plays a unique role in the processing of threat signals by social phobics.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
150 Psychologie
Schlagwörter
Social phobia, fMRI, insula, emotion, task conditions
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690STRAUBE, Thomas, Iris-Tatjana KOLASSA, Madlen GLAUER, Hans-Joachim MENTZEL, Wolfgang H. R. MILTNER, 2004. Effect of Task Conditions on Brain Responses to Threatening Faces in Social Phobics : An Event-Related Functional Magnetic Resonance Imaging Study. In: Biological Psychiatry. 2004, 56, pp. 921-930. Available under: doi: 10.1016/j.biopsych.2004.09.024
BibTex
@article{Straube2004Effec-10280,
  year={2004},
  doi={10.1016/j.biopsych.2004.09.024},
  title={Effect of Task Conditions on Brain Responses to Threatening Faces in Social Phobics : An Event-Related Functional Magnetic Resonance Imaging Study},
  volume={56},
  journal={Biological Psychiatry},
  pages={921--930},
  author={Straube, Thomas and Kolassa, Iris-Tatjana and Glauer, Madlen and Mentzel, Hans-Joachim and Miltner, Wolfgang H. R.}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/10280">
    <dc:contributor>Glauer, Madlen</dc:contributor>
    <dcterms:bibliographicCitation>First publ. in: Biological Psychiatry 56 (2004), pp. 921-930</dcterms:bibliographicCitation>
    <dc:creator>Mentzel, Hans-Joachim</dc:creator>
    <dc:contributor>Miltner, Wolfgang H. R.</dc:contributor>
    <dc:contributor>Straube, Thomas</dc:contributor>
    <dcterms:abstract xml:lang="eng">Background: The aim of this study was to identify brain activation to socially threatening stimuli in social phobic subjects during different experimental conditions.&lt;br /&gt;Methods: With event-related functional magnetic resonance imaging, brain activation to photographs and schematic pictures depicting angry or neutral facial expressions was measured in social phobic subjects and healthy control subjects, while subjects assessed either emotional expression (angry vs. neutral; explicit task) or picture type (photographic vs. schematic; implicit task).&lt;br /&gt;Results: Compared with control subjects, phobics showed greater responses to angry than to neutral photographic faces in the insula regardless of task, whereas amygdala, parahippocampal gyrus, and extrastriate visual cortex were more strongly activated only during the implicit task. Phobics, in contrast to control subjects, showed similar activation patterns during both tasks. For schematic angry versus neutral faces, activation of insula and extrastriate visual cortex was found in phobics, but not in control subjects, during both tasks.&lt;br /&gt;Conclusions: Differences between social phobics and control subjects in brain responses to socially threatening faces are most pronounced when facial expression is task-irrelevant. Phobics intensively process angry (photographic as well as schematic) facial expressions, regardless of whether this is required. The insula plays a unique role in the processing of threat signals by social phobics.</dcterms:abstract>
    <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:title>Effect of Task Conditions on Brain Responses to Threatening Faces in Social Phobics : An Event-Related Functional Magnetic Resonance Imaging Study</dcterms:title>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10280/1/Effect_of_Task_Conditions_on_Brain_Responses_to_Threatening_Faces_in_Social_Phobics.pdf"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:15:41Z</dc:date>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
    <dc:contributor>Mentzel, Hans-Joachim</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10280/1/Effect_of_Task_Conditions_on_Brain_Responses_to_Threatening_Faces_in_Social_Phobics.pdf"/>
    <dc:creator>Kolassa, Iris-Tatjana</dc:creator>
    <dcterms:issued>2004</dcterms:issued>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:15:41Z</dcterms:available>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:format>application/pdf</dc:format>
    <dc:contributor>Kolassa, Iris-Tatjana</dc:contributor>
    <dc:creator>Glauer, Madlen</dc:creator>
    <dc:creator>Straube, Thomas</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:language>eng</dc:language>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/10280"/>
    <dc:creator>Miltner, Wolfgang H. R.</dc:creator>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen