PRES: The Controlled Noninvasive Stimulation of the Carotid Baroreceptors in Humans

Rau, Harald; Elbert, Thomas; Geiger, Bertram; Lutzenberger, Werner

PRES: The Controlled Noninvasive Stimulation of the Carotid Baroreceptors in Humans

Dateien

Elbert_1992_PRES_The_controlled.pdfGröße: 29.66 MBDownloads: 557

Datum

1992

Autor:innen

Rau, Harald

Elbert, Thomas

Geiger, Bertram

Lutzenberger, Werner

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Psychologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Journal of Psychophysiology. 1992, 29(2), pp. 164-172. Available under: doi: 10.1111/j.1469-8986.1992.tb01680.x

Zusammenfassung

To study physiological and psychological effects of baroreceptor activity, the cervical neck cuff technique has been frequently used to stimulate the carotid baroreceptors mechanically. Using this technique, no satisfying control conditions to date have been available. Because the carotid stretch receptors are sensitive not only to the pressure level, but also to the rate of change, it is possible to manipulate the receptor firing through changes in carotid pulse amplitude. The device described here relies on the application of short changes in cuff pressure tied to different phases withing the cardiac cycle (phase related external suction (PRES)). A brief external suction during systole has potent stimulatory effects on baroreceptors whereas the application of the very same pressure pulse during diastole inhibits the firing burst associated with the pulse wave. To allow an ongoing period of stimulation, a sequence of alternating negative/positive pressure pulses is applied. In the stimulation condition, the R-wave of the electrocardiogram triggers a negative pulse which is followed by a positive one during diastole. In the control condition this relationship is reversed. Two experiments are reported confirming different baroreceptor effects of the two conditions. PRES allows for blind or double-blind experiments to investigate effects of baroreceptor activity on physiology and behavior.

Fachgebiet (DDC)

150 Psychologie

Schlagwörter

Baroreceptors, Baroreceptor stimulation, Cervical neck suction, PRES

Zitieren

ISO 690

RAU, Harald, Thomas ELBERT, Bertram GEIGER, Werner LUTZENBERGER, 1992. PRES: The Controlled Noninvasive Stimulation of the Carotid Baroreceptors in Humans. In: Journal of Psychophysiology. 1992, 29(2), pp. 164-172. Available under: doi: 10.1111/j.1469-8986.1992.tb01680.x

BibTex

@article{Rau1992Contr-10508,
  year={1992},
  doi={10.1111/j.1469-8986.1992.tb01680.x},
  title={PRES: The Controlled Noninvasive Stimulation of the Carotid Baroreceptors in Humans},
  number={2},
  volume={29},
  journal={Journal of Psychophysiology},
  pages={164--172},
  author={Rau, Harald and Elbert, Thomas and Geiger, Bertram and Lutzenberger, Werner}
}

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