Mining of Cell Assay Images Using Active Semi-Supervised-Clustering

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2005
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Cebron, Nicolas
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ICDM, pp. 63-69
Zusammenfassung

Classifying large datasets without any a-priori information poses a problem especially in the field of bioinformatics. In this work, we explore the problem of classifying hundreds of thousands of cell assay images obtained by a highthroughput screening camera. The goal is to label a few selected examples by hand and to automatically label the rest of the images afterwards. We deal with three major requirements: first, the model should be easy to understand, second it should offer the possibility to be adjusted by a domain expert, and third the interaction with the user should be kept to a minimum. We propose a new active clustering scheme, based on an initial Fuzzy c-means clustering and Learning Vector Quantization. This scheme can initially cluster large datasets unsupervised and then allows for adjustment of the classification by the user. Furthermore, we introduce a framework for the classification of cell assay images based on this technique. Early experiments show promising results.

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ISO 690CEBRON, Nicolas, Michael R. BERTHOLD, 2005. Mining of Cell Assay Images Using Active Semi-Supervised-Clustering. In: ICDM, pp. 63-69
BibTex
@article{Cebron2005Minin-5769,
  year={2005},
  title={Mining of Cell Assay Images Using Active Semi-Supervised-Clustering},
  journal={ICDM},
  pages={63--69},
  author={Cebron, Nicolas and Berthold, Michael R.}
}
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