Critical Investigation of the CD14 Promoter Polymorphism : Lack of a Role for In Vitro Cytokine Response and Membrane CD14 Expression

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2005
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Rupp, Jan
Gueinzius, Katja
Maass, Matthias
Hermann, Corinna
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Clinical and diagnostic laboratory immunology. 2005, 12(10), pp. 1254-1256. ISSN 1556-6811. Available under: doi: 10.1128/CDLI.12.10.1254-1256.2005
Zusammenfassung

Blood of volunteers, genotyped for the CD14 C(−159)→T polymorphism, showed no difference in cytokine release when stimulated with nine CD14-dependent immune stimuli. An analysis of the published data on the proposed association of CD14 genotype with membrane CD14 density revealed no significant correlation, questioning a functional impact of the CD14 polymorphism.

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570 Biowissenschaften, Biologie
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ISO 690AULOCK, Sonja von, Jan RUPP, Katja GUEINZIUS, Matthias MAASS, Corinna HERMANN, 2005. Critical Investigation of the CD14 Promoter Polymorphism : Lack of a Role for In Vitro Cytokine Response and Membrane CD14 Expression. In: Clinical and diagnostic laboratory immunology. 2005, 12(10), pp. 1254-1256. ISSN 1556-6811. Available under: doi: 10.1128/CDLI.12.10.1254-1256.2005
BibTex
@article{Aulock2005Criti-7025,
  year={2005},
  doi={10.1128/CDLI.12.10.1254-1256.2005},
  title={Critical Investigation of the CD14 Promoter Polymorphism : Lack of a Role for In Vitro Cytokine Response and Membrane CD14 Expression},
  number={10},
  volume={12},
  issn={1556-6811},
  journal={Clinical and diagnostic laboratory immunology},
  pages={1254--1256},
  author={Aulock, Sonja von and Rupp, Jan and Gueinzius, Katja and Maass, Matthias and Hermann, Corinna}
}
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