Error related fields: localizing the magnetic equivalent of the ERN
Dateien
Datum
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
DOI (zitierfähiger Link)
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Sammlungen
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Publikationsstatus
Erschienen in
Zusammenfassung
Introduction:
Research in the field of error processing and error related brain activity has a long history in the field of neuropsychology. It has been found in numerous EEG studies, that a typical brain potential arises following an erroneous response. This error related negativity (ERN) and the accompanying positivity (Pe) are thought to be related to error monitoring and feedback. This is crucial for the detection of errors and correction of actions in the framework of organization of complex behaviors and high-level goals. Yet so far, only a single published study investigated the magnetoencephalographic equivalent to the ERN (mERN) by means of single dipole modeling. This study as well as previous EEG works suggests the major source of the ERN to be located in the anterior cingulate cortex (ACC).
Here, we implemented a computerized version of the paper-and-pencil d2-test, to measure the error related field in the MEG and to localize the generator of the ERN using a distributed source model.
Methods:
13 (5 male/ 8 female) student volunteers participated in this study. We measured the MEG during a 15-minute stimulation period with a 148-channel magnetometer system (MAGNES 2500 WH, 4D Neuroimaging, San Diego, USA). The stimulation consisted of the presentation of the d2-test stimuli and the participants had to indicate via button press whether the stimulus was a d accompanied by two marks or not. Correct and incorrect button presses were recorded. 4 Second snippets around the triggers were extracted and analyzed. Raw data was 1 Hz high pass filtered and trials containing artifacts were excluded from analysis. Trial number in the two conditions was equalized, in order to assure equal signal-to-noise ratio.
After averaging the single trials, a nonparametric permutation test was used to identify clusters of activation in time and sensor space. Subsequently, time-windows of significant effects found in the ERF analysis were modeled in source space using a linearly constrained minimum variance (lcmv) beamformer. Statistical differences on the source level were confirmed using a dependent samples t-test. All analysis steps were performed using Fieldtrip (http://www.ru.nl/neuroimaging/fieldtrip/).
Results:
Cluster analysis revealed a parietal cluster of activation between 80-160 ms after motor response, where the incorrect responses elicited significantly larger field amplitude than the correct responses (p
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
Schlagwörter
Konferenz
Rezension
Zitieren
ISO 690
KEIL, Julian, Nathan WEISZ, Isabella PAUL, Christian WIENBRUCH, 2009. Error related fields: localizing the magnetic equivalent of the ERN. In: NeuroImage. 2009, 47(Suppl. 1), pp. 162. Available under: doi: 10.1016/S1053-8119(09)71715-XBibTex
@article{Keil2009Error-6500, year={2009}, doi={10.1016/S1053-8119(09)71715-X}, title={Error related fields: localizing the magnetic equivalent of the ERN}, number={Suppl. 1}, volume={47}, journal={NeuroImage}, author={Keil, Julian and Weisz, Nathan and Paul, Isabella and Wienbruch, Christian} }
RDF
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/6500"> <dc:creator>Keil, Julian</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/> <dc:contributor>Keil, Julian</dc:contributor> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6500/1/Poster_2A0_HBMI_ver3_1.pdf"/> <dc:contributor>Paul, Isabella</dc:contributor> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/6500/1/Poster_2A0_HBMI_ver3_1.pdf"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/6500"/> <dcterms:title>Error related fields: localizing the magnetic equivalent of the ERN</dcterms:title> <dcterms:issued>2009</dcterms:issued> <dc:creator>Weisz, Nathan</dc:creator> <dc:contributor>Wienbruch, Christian</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/"/> <dc:contributor>Weisz, Nathan</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:05:39Z</dcterms:available> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/> <dc:creator>Paul, Isabella</dc:creator> <dc:creator>Wienbruch, Christian</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:language>eng</dc:language> <dcterms:bibliographicCitation>First publ. in: NeuroImage 47 (2009), Suppl. 1, p.162</dcterms:bibliographicCitation> <dc:format>application/pdf</dc:format> <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights> <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:05:39Z</dc:date> <dcterms:abstract xml:lang="eng">Introduction:<br />Research in the field of error processing and error related brain activity has a long history in the field of neuropsychology. It has been found in numerous EEG studies, that a typical brain potential arises following an erroneous response. This error related negativity (ERN) and the accompanying positivity (Pe) are thought to be related to error monitoring and feedback. This is crucial for the detection of errors and correction of actions in the framework of organization of complex behaviors and high-level goals. Yet so far, only a single published study investigated the magnetoencephalographic equivalent to the ERN (mERN) by means of single dipole modeling. This study as well as previous EEG works suggests the major source of the ERN to be located in the anterior cingulate cortex (ACC).<br />Here, we implemented a computerized version of the paper-and-pencil d2-test, to measure the error related field in the MEG and to localize the generator of the ERN using a distributed source model.<br />Methods:<br />13 (5 male/ 8 female) student volunteers participated in this study. We measured the MEG during a 15-minute stimulation period with a 148-channel magnetometer system (MAGNES 2500 WH, 4D Neuroimaging, San Diego, USA). The stimulation consisted of the presentation of the d2-test stimuli and the participants had to indicate via button press whether the stimulus was a d accompanied by two marks or not. Correct and incorrect button presses were recorded. 4 Second snippets around the triggers were extracted and analyzed. Raw data was 1 Hz high pass filtered and trials containing artifacts were excluded from analysis. Trial number in the two conditions was equalized, in order to assure equal signal-to-noise ratio.<br />After averaging the single trials, a nonparametric permutation test was used to identify clusters of activation in time and sensor space. Subsequently, time-windows of significant effects found in the ERF analysis were modeled in source space using a linearly constrained minimum variance (lcmv) beamformer. Statistical differences on the source level were confirmed using a dependent samples t-test. All analysis steps were performed using Fieldtrip (http://www.ru.nl/neuroimaging/fieldtrip/).<br />Results:<br />Cluster analysis revealed a parietal cluster of activation between 80-160 ms after motor response, where the incorrect responses elicited significantly larger field amplitude than the correct responses (p</dcterms:abstract> </rdf:Description> </rdf:RDF>