Enzymatic synthesis of peptides on a solid support

Haddoub, Rose; Dauner, Martin; Stefanowicz, Fiona A.; Barattini, Valeria; Laurent, Nicolas; Flitsch, Sabine L.

Enzymatic synthesis of peptides on a solid support

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2009

Autor:innen

Haddoub, Rose

Dauner, Martin

Stefanowicz, Fiona A.

Barattini, Valeria

Laurent, Nicolas

Flitsch, Sabine L.

URI (zitierfähiger Link)

http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-90953

DOI (zitierfähiger Link)

https://doi.org/10.1039/B816847D

Projekt

Chemische Werkzeuge zur Untersuchung der Zusammensetzung und Dynamik von Lipidmikrodomänen in lebenden Zellen

Sammlungen

Zukunftskolleg
Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Organic & Biomolecular Chemistry. 2009, 7(4), pp. 665-670. Available under: doi: 10.1039/B816847D

Zusammenfassung

We have previously shown that dipeptides can be synthesised in high yields from amino acids using protease catalysis in aqueous media, if the amino component is immobilised on porous PEGA resin (a copolymer of polyethylene glycol and polyacrylamide). Here we explore the scope of this methodology for using protected and glycosylated amino acids as well as the synthesis of longer peptides on resin and show that such a method can also be applied on non-porous surfaces, in particular on gold.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

HADDOUB, Rose, Martin DAUNER, Fiona A. STEFANOWICZ, Valeria BARATTINI, Nicolas LAURENT, Sabine L. FLITSCH, 2009. Enzymatic synthesis of peptides on a solid support. In: Organic & Biomolecular Chemistry. 2009, 7(4), pp. 665-670. Available under: doi: 10.1039/B816847D

BibTex

@article{Haddoub2009Enzym-3304,
  year={2009},
  doi={10.1039/B816847D},
  title={Enzymatic synthesis of peptides on a solid support},
  number={4},
  volume={7},
  journal={Organic & Biomolecular Chemistry},
  pages={665--670},
  author={Haddoub, Rose and Dauner, Martin and Stefanowicz, Fiona A. and Barattini, Valeria and Laurent, Nicolas and Flitsch, Sabine L.}
}

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