Please use this persistent identifier to cite or link to this item: doi:10.24405/573
Title: Fundamental studies of affinity separation of glycoproteins and its combination with expanded bed adsorption technique
Authors: Wen, Zhenzhen
Language: eng
Keywords: Affinitätstrennung;Expanded Bed Adsorption;Concanavalin A;Glucoseoxidase
Subject (DDC): 600 Technik
Issue Date: 2006
Publisher: Universitätsbibliothek der HSU / UniBwH
Document Type: Thesis
Publisher Place: Hamburg
Abstract: 
This work concerns the fundamental aspects of affinity separation of glycoconjugates, in particular, glycoproteins such as the enzyme glucose oxidase (GOD). It includes studies on the adsorption behaviour of GOD onto Concanavalin A (Con A) adsorbents, the preparation, characterization, and properties investigation of PEGylated Con A, the characterization of novel dense pellicular agarose coated glass beads and its application for expanded bed adsorption of proteins.

Diese Arbeit behandelt die fundamentalen Aspekte der Affinitätstrennung von Glykokonjugaten, insbesondere von Glykoproteinen am Beispiel des Enzym Glucose Oxidase (GOD). Die Studien beinhalten das Adsorptionsverhalten von GOD an Concanavalin A (ConA) Adsorbentien, deren Herstellung und Eigenschaften sowie Untersuchungen von PEGyliertem Con A und der Charakterisierung von einer neuen Matrix, die aus Agarose beschichteten Glasperlen (AG) besteht, und deren Einsatz in der Proteinadsorption mittels Expanded bed adsorption.
Organization Units (connected with the publication): Verfahrenstechnik, insb. Stofftrennung 
DOI: https://doi.org/10.24405/573
Advisor: Niemeyer, Bernd
Grantor: HSU Hamburg
Type of thesis: Doctoral Thesis
Exam date: 2006-08-02
Appears in Collections:2 - Theses

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