Cammarota, Giovanni, Ianiro, Gianluca ORCID: 0000-0002-8318-0515, Kelly, Colleen R., Mullish, Benjamin H., Allegretti, Jessica R., Kassam, Zain, Putignani, Lorenza, Fischer, Monika, Keller, Josbert J., Costello, Samuel Paul, Sokol, Harry, Kump, Patrizia, Satokari, Reetta, Kahn, Stacy A., Kao, Dina, Arkkila, Perttu, Kuijper, Ed J., Vehreschild, Maria J. G. T., Pintus, Cristina, Lopetuso, Loris, Masucci, Luca ORCID: 0000-0002-8358-6726, Scaldaferri, Franco, Terveer, E. M., Nieuwdorp, Max, Lopez-Sanroman, Antonio, Kupcinskas, Juozas, Hart, Ailsa, Tilg, Herbert and Gasbarrini, Antonio (2019). International consensus conference on stool banking for faecal microbiota transplantation in clinical practice. Gut, 68 (12). S. 2111 - 2122. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-3288

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Abstract

Although faecal microbiota transplantation (FMT) has a well-established role in the treatment of recurrent Clostridioides difficile infection (CDI), its widespread dissemination is limited by several obstacles, including lack of dedicated centres, difficulties with donor recruitment and complexities related to regulation and safety monitoring. Given the considerable burden of CDI on global healthcare systems, FMT should be widely available to most centres. Stool banks may guarantee reliable, timely and equitable access to FMT for patients and a traceable workflow that ensures safety and quality of procedures. In this consensus project, FMT experts from Europe, North America and Australia gathered and released statements on the following issues related to the stool banking: general principles, objectives and organisation of the stool bank; selection and screening of donors; collection, preparation and storage of faeces; services and clients; registries, monitoring of outcomes and ethical issues; and the evolving role of FMT in clinical practice, Consensus on each statement was achieved through a Delphi process and then in a plenary face-to-face meeting. For each key issue, the best available evidence was assessed, with the aim of providing guidance for the development of stool banks in order to promote accessibility to FMT in clinical practice.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Cammarota, GiovanniUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ianiro, GianlucaUNSPECIFIEDorcid.org/0000-0002-8318-0515UNSPECIFIED
Kelly, Colleen R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mullish, Benjamin H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Allegretti, Jessica R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kassam, ZainUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Putignani, LorenzaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fischer, MonikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Keller, Josbert J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Costello, Samuel PaulUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sokol, HarryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kump, PatriziaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Satokari, ReettaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kahn, Stacy A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kao, DinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arkkila, PerttuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuijper, Ed J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vehreschild, Maria J. G. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pintus, CristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lopetuso, LorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Masucci, LucaUNSPECIFIEDorcid.org/0000-0002-8358-6726UNSPECIFIED
Scaldaferri, FrancoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Terveer, E. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nieuwdorp, MaxUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lopez-Sanroman, AntonioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kupcinskas, JuozasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hart, AilsaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tilg, HerbertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gasbarrini, AntonioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-125763
DOI: 10.1136/gutjnl-2019-319548
Journal or Publication Title: Gut
Volume: 68
Number: 12
Page Range: S. 2111 - 2122
Date: 2019
Publisher: BMJ PUBLISHING GROUP
Place of Publication: LONDON
ISSN: 1468-3288
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
CLOSTRIDIUM-DIFFICILE INFECTION; ACTIVE ULCERATIVE-COLITIS; INTESTINAL MICROBIOTA; INSULIN SENSITIVITY; ORGAN DONATION; DONOR FECES; RECURRENT; EFFICACY; FROZEN; METAANALYSISMultiple languages
Gastroenterology & HepatologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/12576

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