Universität zu Köln

Vitinius, Frank, Reklat, Andre, Hellmich, Martin, Klask, Elisa, Wahlers, Thorsten, Rahmanian, Parwis B. ORCID: 0000-0002-3978-9251, Pfister, Roman, Mueller-Ehmsen, Jochen and Albus, Christian (2019). Prediction of survival on the waiting list for heart transplantation and of posttransplant nonadherence-Results of a prospective longitudinal study. Clin. Transplant., 33 (7). HOBOKEN: WILEY. ISSN 1399-0012

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Abstract

Background Only a few previous studies have focused on the interaction between pretransplant psychological variables, survival on the waiting list, and adherence to therapy after heart transplantation (HTx). Methods This work combined two studies: Study 1 monitored survival of patients on a HTx waiting list (n = 50) and study 2 examined barriers to adherence after HTx (subgroup of n = 20). All patients were evaluated immediately after listing for HTx (T0). Those in study 2 were also evaluated immediately after HTx (T1) and after 6 months (T2). Psychosocial functioning was measured by the Transplant Evaluation Rating Scale (TERS), and depression and anxiety by Patient Health Questionnaire and Hospital Anxiety and Depression Scale. Barriers to immunosuppressive adherence post-HTx were measured by the Medication Experience Scale for Immunosuppressants (MESI). Results According to the TERS classification of Rothenhausler et al, patients were divided into three groups in study 1. Compared with inconspicuous patients (n = 23) and risk patients (n = 21), high-risk patients (n = 6) demonstrated a higher mortality (log-rank test of trend, P = 0.002). In study 2, there was a strong correlation between the TERS (T0) and the MESI (T2) (r = 0.84, P = 0.001). Conclusions The TERS may serve as a predictor of survival on the waiting list. There is need for further longitudinal data with larger sample sizes.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Vitinius, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Reklat, Andre UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Klask, Elisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahmanian, Parwis B. UNSPECIFIED orcid.org/0000-0002-3978-9251 UNSPECIFIED Pfister, Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller-Ehmsen, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED Albus, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-136161
DOI:	10.1111/ctr.13616
Journal or Publication Title:	Clin. Transplant.
Volume:	33
Number:	7
Date:	2019
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1399-0012
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EVALUATION RATING-SCALE; QUALITY-OF-LIFE; PSYCHOSOCIAL EVALUATION; DEPRESSIVE SYMPTOMS; HOSPITAL ANXIETY; MEDICATION; LIVER; CANDIDATES; ATTITUDES; INSTRUMENT Multiple languages Surgery; Transplantation Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13616