Escher, Claus M., Sannemann, Lena and Jessen, Frank (2019). Stress and Alzheimer's disease. J. Neural Transm., 126 (9). S. 1155 - 1162. WIEN: SPRINGER WIEN. ISSN 1435-1463

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Abstract

Alzheimer's disease (AD) is the leading cause of dementia worldwide. Due to demographic change in higher income countries and rising life expectancy in middle- and low-income countries, the prevalence of AD will increase significantly in the coming years. In the search for effective AD prevention, the role of stress in the development of AD has come into focus. There is increasing evidence that chronic exposure to stress is a risk factor for AD and may also adversely affect the course of the disease. In our review, we present the current literature on the association of specific personality traits and the risk of developing AD. We also report on findings on dementia risk in patients with posttraumatic stress disorder. Furthermore, we describe the role of anxiety symptoms in AD and give a brief overview over the biological mechanisms behind the association of stress and AD.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Escher, Claus M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sannemann, LenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jessen, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-142646
DOI: 10.1007/s00702-019-01988-z
Journal or Publication Title: J. Neural Transm.
Volume: 126
Number: 9
Page Range: S. 1155 - 1162
Date: 2019
Publisher: SPRINGER WIEN
Place of Publication: WIEN
ISSN: 1435-1463
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MILD COGNITIVE IMPAIRMENT; NEUROPSYCHIATRIC SYMPTOMS; ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; PSYCHOLOGICAL DISTRESS; PRECLINICAL PHASE; TAU PATHOLOGY; AMYLOID-BETA; DEMENTIAMultiple languages
Clinical Neurology; NeurosciencesMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14264

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