Universität zu Köln

Schuessler, Stephanie C., Kussmann, Franziska, Fahlbusch, Fabian B., Muenster, Tino, Hirsch, Karin, Carbon, Roman, Albrecht, Sven, Doetsch, Joerg and Rascher, Wolfgang (2019). Postoperative pain in small-for-gestational age infants after hernia repair, orchidopexy and urethral reconstruction surgery: A pilot study. Early Hum. Dev., 136. S. 39 - 45. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-6232

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Abstract

Background: Small-for-gestational-age (SGA) birth bears an enhanced risk of developing hypertension, obesity, insulin resistance and mental health disorders in later life as a consequence of adaptive processes in utero. Only a small number of studies on pain perception in SGA infants exist. These are indicative of a blunted stress response to pain in SGA newborns. Aim: We initiated a pilot study investigating differences in postoperative pain perception between SGA and appropriate-for-gestational-age (AGA) infants. Methods: Pain and alertness levels of 10 formerly SGA and 14 AGA infants at the age 0.5-2 years were evaluated by the FLACC scale, Steward and Aldrete Scores following hernia repair, reconstructive surgery of hypospadia and orchidopexy. In addition, the postoperative consumption of non-steroidal anti-inflammatory drugs was compared between SGA and AGA. Results: Postoperative pain and alertness levels were not significantly different in SGA and AGA children. We did not observe significant group differences regarding the consumption of non-steroidal anti-inflammatory drugs. Conclusion: While previous studies were suggestive of a suppressed stress response to pain in SGA newborns, these findings did not fully translate into an altered response to pain beyond the newborn age. Further studies in a larger cohort seem necessary to verify this finding.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schuessler, Stephanie C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kussmann, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Fahlbusch, Fabian B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Muenster, Tino UNSPECIFIED UNSPECIFIED UNSPECIFIED Hirsch, Karin UNSPECIFIED UNSPECIFIED UNSPECIFIED Carbon, Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Albrecht, Sven UNSPECIFIED UNSPECIFIED UNSPECIFIED Doetsch, Joerg UNSPECIFIED UNSPECIFIED UNSPECIFIED Rascher, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-143352
DOI:	10.1016/j.earlhumdev.2019.07.003
Journal or Publication Title:	Early Hum. Dev.
Volume:	136
Page Range:	S. 39 - 45
Date:	2019
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1872-6232
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LOW-BIRTH-WEIGHT; IMPAIRED GLUCOSE-TOLERANCE; INTRAUTERINE GROWTH; CORTISOL CONCENTRATIONS; RISK; PRETERM; STRESS; TYPE-2; FETAL; ADULTS Multiple languages Obstetrics & Gynecology; Pediatrics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14335