Universität zu Köln

Saville, Christopher W. N., de Morree, H. M., Dundon, Neil M., Marcora, S. M. and Klein, C. (2018). Effects of caffeine on reaction time are mediated by attentional rather than motor processes. Psychopharmacology, 235 (3). S. 749 - 760. NEW YORK: SPRINGER. ISSN 1432-2072

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Abstract

In the present study, 15 female participants performed an oddball task after ingesting caffeine or a placebo, and electroencephalographic data were obtained. Single-trial P3b latencies locked to the stimulus and to the response were extracted and mediation models were fitted to the data to test whether caffeine's effect on RTs was mediated by its effect on either type of P3b latencies. These findings are consistent with caffeine's effect on RTs being a result of its effect on perceptual-attentional processes, rather than motor processes. The study is the first to apply mediation analysis to single-trial P3b data and this technique holds promise for mental chronometric studies into the effects of psychopharmacological agents. The R code for performing the single trial analysis and mediation analysis are included as supplementary materials.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Saville, Christopher W. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED de Morree, H. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dundon, Neil M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Marcora, S. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klein, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-195098
DOI:	10.1007/s00213-017-4790-7
Journal or Publication Title:	Psychopharmacology
Volume:	235
Number:	3
Page Range:	S. 749 - 760
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-2072
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LATENCY VARIABILITY; WORKING-MEMORY; NON-CONSUMERS; PERFORMANCE; MOOD; P3B; ADENOSINE; P300; RECEPTORS; INSIGHTS Multiple languages Neurosciences; Pharmacology & Pharmacy; Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19509