Universität zu Köln

Godet, Cendrine, Alastruey-Izquierdo, Ana ORCID: 0000-0001-8651-4405, Flick, Holger, Hennequin, Christophe, Mikilps-Mikgelbs, Rihards, Munteanu, Oxana ORCID: 0000-0001-5911-9426, Page, Iain, Seidel, Danila ORCID: 0000-0003-4388-3117 and Salzer, Helmut J. F. (2018). A CPAnet consensus statement on research priorities for chronic pulmonary aspergillosis: a neglected fungal infection that requires attention. J. Antimicrob. Chemother., 73 (2). S. 280 - 287. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2091

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Abstract

Chronic pulmonary aspergillosis (CPA) is a severe fungal infection with a high morbidity and mortality, and is usually seen in immunocompetent patients with respiratory disorders. Clinical presentation is nonspecific and often overlaps with the symptoms and the radiological pattern caused by the underlying disease. Clinical management of CPA is further hampered by limited information about the epidemiology, disease dynamics, sensitivity and specificity of different mycological tests, mechanisms of antifungal resistance, efficient treatment and management strategies. In order to contribute to a better understanding and to improve CPA patient management and outcome, we established the Chronic Pulmonary Aspergillosis Network (CPAnet), a self-organized multinational research collaboration. Key research priorities, defined by using a modified Delphi process, include the establishment of a multinational web-based registry, the validation of different diagnostic tests, the establishment of a culture collection from samples of patients with proven CPA and the establishment of a consensus on a treatment outcome definition.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Godet, Cendrine UNSPECIFIED UNSPECIFIED UNSPECIFIED Alastruey-Izquierdo, Ana UNSPECIFIED orcid.org/0000-0001-8651-4405 UNSPECIFIED Flick, Holger UNSPECIFIED UNSPECIFIED UNSPECIFIED Hennequin, Christophe UNSPECIFIED UNSPECIFIED UNSPECIFIED Mikilps-Mikgelbs, Rihards UNSPECIFIED UNSPECIFIED UNSPECIFIED Munteanu, Oxana UNSPECIFIED orcid.org/0000-0001-5911-9426 UNSPECIFIED Page, Iain UNSPECIFIED UNSPECIFIED UNSPECIFIED Seidel, Danila UNSPECIFIED orcid.org/0000-0003-4388-3117 UNSPECIFIED Salzer, Helmut J. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-196500
DOI:	10.1093/jac/dkx390
Journal or Publication Title:	J. Antimicrob. Chemother.
Volume:	73
Number:	2
Page Range:	S. 280 - 287
Date:	2018
Publisher:	OXFORD UNIV PRESS
Place of Publication:	OXFORD
ISSN:	1460-2091
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CLINICAL CHARACTERISTICS; CHRONIC CAVITARY; DIAGNOSIS; VORICONAZOLE; ITRACONAZOLE; EFFICACY; MICAFUNGIN; SAFETY; ASSAYS; GALACTOMANNAN Multiple languages Infectious Diseases; Microbiology; Pharmacology & Pharmacy Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19650