Universität zu Köln

Mkalaluh, Sabreen, Szczechowicz, Marcin, Torabi, Saeed, Schmack, Bastian, Sabashnikov, Anton, Dib, Bashar, Karck, Matthias and Weymann, Alexander (2017). Surgical Treatment of Cardiac Tumors: Insights from an 18-Year Single-Center Analysis. Med. Sci. Monitor, 23. S. 6201 - 6210. SMITHTOWN: INT SCIENTIFIC LITERATURE, INC. ISSN 1643-3750

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Abstract

Background: The aim of this study was to investigate the clinical presentation, operative data, and early and late outcomes of a large patient cohort undergoing surgical treatment for cardiac tumors in our institution. Material/Methods: A total of 181 patients underwent surgery because of suspected cardiac tumor in our institution between 1998 and 2016. In 162 cases, the diagnosis was confirmed postoperatively and these patients were included in this study. Preoperative baseline characteristics, operative data, and postoperative early and long-term outcomes were analyzed. Results: Mean age at presentation was 56.6 +/- 17.6 years, and 95 (58.6%) patients were female. There were 126 (77.8%) patients with benign cardiac tumors, while the remaining patients had malignant tumors (primary and metastasized). The mean follow-up time was 5.2 +/- 4.7 years. The most frequent histologically verified tumor type was myxoma (63%, n=102). In terms of malignant tumors, various types of sarcomas presented most primary malignant cardiac tumors (7.4%, n=12). The mean ICU length of stay was 1.7 +/- 2.2 days and overall in-hospital mortality was 3.1% (n=5). Frequent postoperative complications included mediastinal bleeding (5.8%, n=9), wound infection (1.3%, n=2), acute renal failure (5.6%, n=9), and major cerebrovascular events (n=7, 4.6%). The overall cumulative survival after cardiac tumor resection was 94% at 30 days, 85% at 1 year, 72% at 5 years, and 59% at 15 years. Conclusions: Surgical treatment of cardiac tumors is a safe and highly effective strategy associated with good early and longterm outcomes.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mkalaluh, Sabreen UNSPECIFIED UNSPECIFIED UNSPECIFIED Szczechowicz, Marcin UNSPECIFIED UNSPECIFIED UNSPECIFIED Torabi, Saeed UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmack, Bastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Dib, Bashar UNSPECIFIED UNSPECIFIED UNSPECIFIED Karck, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Weymann, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-207580
DOI:	10.12659/MSM.905451
Journal or Publication Title:	Med. Sci. Monitor
Volume:	23
Page Range:	S. 6201 - 6210
Date:	2017
Publisher:	INT SCIENTIFIC LITERATURE, INC
Place of Publication:	SMITHTOWN
ISSN:	1643-3750
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MALIGNANT-TUMORS; EXPERIENCE; HEART; DIAGNOSIS; RESECTION; SARCOMAS; MYXOMAS; MANAGEMENT; SURVIVAL; THERAPY Multiple languages Medicine, Research & Experimental Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20758