Meyer, M. F., Kreppel, M., Meinrath, J., Gruunewald, I, Stenner, M., Drebber, U., Quaas, A., Odenthal, M., Semrau, R., Huebbers, C. U., Zoeller, J., Huettenbrink, K-B, Buettner, R. and Beutner, D. (2017). Prediction of outcome by lymph node ratio in patients with parotid gland cancer. Clin. Otolaryngol., 42 (1). S. 98 - 104. HOBOKEN: WILEY. ISSN 1749-4486

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Abstract

Objective: Lymph node ratio (LNR) has been shown to be an independent predictor of recurrence risk and survival in different entities of carcinoma. Methods: In this retrospective chart review, 128 patients with parotid gland cancer (PGC) subsequently treated by primary surgery were included. About 64% (n = 82) of these patients were additionally treated with adjuvant radiotherapy. Five-year overall survival rates were determined by subgroups based on LNR value. Results: Lymph node ratio was found to be significantly associated with overall survival rate (P < 0.001). Using univariate analyses, pathological tumour-node-metastasis (TNM)-stage, UICC-stage grouping and extracapsular spread were found to be significant predictors of overall survival (P < 0.001). However, with a multivariate analyses, LNR remained the only independent predictor of overall survival (P = 0.043). Conclusions: After surgery for PGC, evaluation of the neck using LNR was found to reliably stratify the overall survival rate.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Meyer, M. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreppel, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meinrath, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gruunewald, IUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stenner, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Drebber, U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Quaas, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Odenthal, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Semrau, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huebbers, C. U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zoeller, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huettenbrink, K-BUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buettner, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beutner, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-240345
DOI: 10.1111/coa.12672
Journal or Publication Title: Clin. Otolaryngol.
Volume: 42
Number: 1
Page Range: S. 98 - 104
Date: 2017
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1749-4486
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ORAL-CAVITY CANCER; PROGNOSTIC-FACTORS; DENMARK 1990-2005; NECK DISSECTION; DANISH HEAD; DENSITY; CARCINOMA; METASTASIS; SURVIVAL; PATTERNMultiple languages
OtorhinolaryngologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/24034

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