Mueller, U. J., Sturm, V., Voges, J., Heinze, H-J, Galazky, I., Buentjen, L., Heldmann, M., Frodl, T., Steiner, J. and Bogerts, B. (2016). Nucleus Accumbens Deep Brain Stimulation for Alcohol Addiction - Safety and Clinical Long-term Results of a Pilot Trial. Pharmacopsychiatry, 49 (4). S. 170 - 174. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-0795

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Abstract

We report on the long-term clinical outcome (up to 8 years) of 5 patients who received deep brain stimulation (DBS) of the nucleus accumbens to treat their long-lasting and treatment-resistant alcohol addiction. All patients reported a complete absence of craving for alcohol; 2 patients remained abstinent for many years and 3 patients showed a marked reduction of alcohol consumption. No severe or long-standing side effects occurred. Therefore, DBS could be a promising, novel treatment option for severe alcohol addiction, but larger clinical trials are needed to further investigate the efficacy of DBS in addiction.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Mueller, U. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sturm, V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Voges, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heinze, H-JUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Galazky, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buentjen, L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heldmann, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frodl, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steiner, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bogerts, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-270734
DOI: 10.1055/s-0042-104507
Journal or Publication Title: Pharmacopsychiatry
Volume: 49
Number: 4
Page Range: S. 170 - 174
Date: 2016
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 1439-0795
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
DRUG-ADDICTION; USE DISORDERS; METAANALYSIS; MORTALITYMultiple languages
Pharmacology & Pharmacy; PsychiatryMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/27073

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