Universität zu Köln

Bedard, A., Basagana, X., Anto, J. M., Garcia-Aymerich, J., Devillier, P., Arnavielhe, S., Bedbrook, A., Onorato, G. L., Czarlewski, W., Murray, R., Almeida, R., Fonseca, J. A., Correia da Sousa, J., Costa, E., Morais-Almeida, M., Todo-Bom, A., Cecchi, L., De Feo, G., Illario, M., Menditto, E., Monti, R., Stellato, C., Ventura, M. T., Annesi-Maesano, I, Bosse, I, Fontaine, J. F., Pham-Thi, N., Thibaudon, M., Schmid-Grendelmeier, P., Spertini, F., Chavannes, N. H., Fokkens, W. J., Reitsma, S., Dubakiene, R., Emuzyte, R., Kvedariene, V, Valiulis, A., Kuna, P., Samolinski, B., Klimek, L., Moesges, R., Pfaar, O., Shamai, S., Roller-Wirnsberger, R. E., Tomazic, P., V, Ryan, D., Sheikh, A., Haahtela, T., Toppila-Salmi, S., Valovirta, E., Cardona, V, Mullol, J., Valero, A., Makris, M., Papadopoulos, N. G., Prokopakis, E. P., Psarros, F., Bachert, C., Hellings, P. W., Pugin, B., Bindslev-Jensen, C., Eller, E., Kull, I, Melen, E., Wickman, M., De Vries, G., van Eerd, M., Agache, I, Ansotegui, I. J., Bosnic-Anticevich, S., Cruz, A. A., Casale, T., Ivancevich, J. C., Larenas-Linnemann, D. E., Sofev, M., Wallace, D., Waserman, S., Yorgancioglu, A., Laune, D. and Bousquet, J. (2020). Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study. Clin. Transl. Allergy, 10 (1). LONDON: BMC. ISSN 2045-7022

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Abstract

Background The analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world observational study was undertaken in 17 European countries during and outside the estimated pollen season. The aim was to collect novel information including the phenotypic characteristics of the users. Methods The Allergy Diary-MASK-air-mobile phone app, freely available via Google Play and App, was used to collect the data of daily visual analogue scales (VASs) for overall allergic symptoms and medication use. Fluticasone Furoate (FF), Mometasone Furoate (MF), Azelastine Fluticasone Proprionate combination (MPAzeFlu) and eight oral H1-antihistamines were studied. Phenotypic characteristics were recorded at entry. The ARIA severity score was derived from entry data. This was an a priori planned analysis. Results 9037 users filled in 70,286 days of VAS in 2016, 2017 and 2018. The ARIA severity score was lower outside than during the pollen season. Severity was similar for all treatment groups during the pollen season, and lower in the MPAzeFlu group outside the pollen season. Days with MPAzeFlu had lower VAS levels and a higher frequency of monotherapy than the other treatments during the season. Outside the season, days with MPAzeFlu also had a higher frequency of monotherapy. The number of reported days was significantly higher with MPAzeFlu during and outside the season than with MF, FF or oral H1-antihistamines. Conclusions This study shows that the overall efficacy of treatments is similar during and outside the pollen season and indicates that medications are similarly effective during the year.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bedard, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Basagana, X. UNSPECIFIED UNSPECIFIED UNSPECIFIED Anto, J. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Garcia-Aymerich, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Devillier, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Arnavielhe, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bedbrook, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Onorato, G. L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Czarlewski, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Murray, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Almeida, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fonseca, J. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Correia da Sousa, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Costa, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Morais-Almeida, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Todo-Bom, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cecchi, L. UNSPECIFIED UNSPECIFIED UNSPECIFIED De Feo, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Illario, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Menditto, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Monti, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stellato, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ventura, M. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Annesi-Maesano, I UNSPECIFIED UNSPECIFIED UNSPECIFIED Bosse, I UNSPECIFIED UNSPECIFIED UNSPECIFIED Fontaine, J. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pham-Thi, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Thibaudon, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmid-Grendelmeier, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Spertini, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Chavannes, N. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fokkens, W. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Reitsma, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dubakiene, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Emuzyte, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kvedariene, V UNSPECIFIED UNSPECIFIED UNSPECIFIED Valiulis, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuna, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Samolinski, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klimek, L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moesges, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfaar, O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Shamai, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Roller-Wirnsberger, R. E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Tomazic, P., V UNSPECIFIED UNSPECIFIED UNSPECIFIED Ryan, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sheikh, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Haahtela, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Toppila-Salmi, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Valovirta, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cardona, V UNSPECIFIED UNSPECIFIED UNSPECIFIED Mullol, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Valero, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Makris, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Papadopoulos, N. G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Prokopakis, E. P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Psarros, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachert, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellings, P. W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pugin, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bindslev-Jensen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Eller, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kull, I UNSPECIFIED UNSPECIFIED UNSPECIFIED Melen, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wickman, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED De Vries, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED van Eerd, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Agache, I UNSPECIFIED UNSPECIFIED UNSPECIFIED Ansotegui, I. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bosnic-Anticevich, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cruz, A. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Casale, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ivancevich, J. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Larenas-Linnemann, D. E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sofev, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wallace, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Waserman, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Yorgancioglu, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Laune, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bousquet, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-308440
DOI:	10.1186/s13601-020-00342-x
Journal or Publication Title:	Clin. Transl. Allergy
Volume:	10
Number:	1
Date:	2020
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	2045-7022
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PERSON-CENTERED CARE; AIR-POLLUTION; ASTHMA; IMPACT; INTERMITTENT; IMPAIRMENT; SEVERITY; GUIDANCE Multiple languages Allergy Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/30844