Oertel, M., Elsayad, K., Engenhart-Cabillic, R., Reinartz, G., Baues, C., Schmidberger, H., Vordermark, D., Marnitz, S., Lukas, P., Ruebe, C., Engert, A., Lenz, G. and Eich, H. T. (2020). Radiation treatment of hemato-oncological patients in times of the COVID-19 pandemic Expert recommendations from the radiation oncology panels of the German Hodgkin Study Group and the German Lymphoma Alliance. Strahlenther. Onkol., 196 (12). S. 1096 - 1103. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1439-099X

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Abstract

Purpose The coronavirus pandemic is affecting global health systems, endangering daily patient care. Hemato-oncological patients are particularly vulnerable to infection, requiring decisive recommendations on treatment and triage. The aim of this survey amongst experts on radiation therapy (RT) for lymphoma and leukemia is to delineate typical clinical scenarios and to provide counsel for high-quality care. Methods A multi-item questionnaire containing multiple-choice and free-text questions was developed in a peer-reviewed process and sent to members of the radiation oncology panels of the German Hodgkin Study Group and the German Lymphoma Alliance. Answers were assessed online and analyzed centrally. Results Omission of RT was only considered in a minority of cases if alternative treatment options were available. Hypofractionated regimens and reduced dosages may be used for indolent lymphoma and fractures due to multiple myeloma. Overall, there was a tendency to shorten RT rather than to postpone or omit it. Even in case of critical resource shortage, panelists agreed to start emergency RT for typical indications (intracranial pressure, spinal compression, superior vena cava syndrome) within 24-h. Possible criteria to consider for patient triage are the availability of (systemic) options, the underlying disease dynamic, and the treatment rationale (curative/palliative). Conclusion RT for hemato-oncological patients receives high-priority and should be maintained even in later stages of the pandemic. Hypofractionation and shortened treatment schedules are feasible options for well-defined constellations, but have to be discussed in the clinical context.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Oertel, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Elsayad, K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Engenhart-Cabillic, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reinartz, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baues, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmidberger, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vordermark, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marnitz, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lukas, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ruebe, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Engert, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lenz, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eich, H. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-314027
DOI: 10.1007/s00066-020-01705-w
Journal or Publication Title: Strahlenther. Onkol.
Volume: 196
Number: 12
Page Range: S. 1096 - 1103
Date: 2020
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1439-099X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
DOSE RADIOTHERAPY; THERAPY; PLASMACYTOMA; GUIDELINESMultiple languages
Oncology; Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/31402

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