Universität zu Köln

Alberici, Irene, Bayazit, Aysun Karabay, Drozdz, Dorota, Emre, Sevinc, Fischbach, Michel, Harambat, Jerome, Jankauskiene, Augustina, Litwin, Mieczyslaw ORCID: 0000-0002-5241-2483, Mir, Sevgi, Morello, William ORCID: 0000-0002-4833-4128, Peco-Antic, Amira, Sallay, Peter, Sever, Lale, Simonetti, Giacomo D., Szczesniak, Przemyslaw, Teixeira, Ana, Vidal, Enrico ORCID: 0000-0003-3963-0803, Wuehl, Elke, Mehls, Otto, Weber, Lutz T., Schaefer, Franz and Montini, Giovanni ORCID: 0000-0002-7350-4475 (2015). Pathogens causing urinary tract infections in infants: a European overview by the ESCAPE study group. Eur. J. Pediatr., 174 (6). S. 783 - 791. NEW YORK: SPRINGER. ISSN 1432-1076

Full text not available from this repository.

Abstract

Knowledge of the distribution spectrum of causative organisms and their resistance patterns has become a core requirement for the rational and effective management of urinary tract infections. In the context of a prospective trial on the use of antibiotic prophylaxis in infants with underling kidney malformations, we conducted an online survey among paediatric nephrologists on positive urine cultures (July 2010-June 2012) from both hospitalized and non-hospitalized infants under 24 months of age. We collected 4745 urine cultures (UCs) at 18 units in 10 European countries. Escherichia coli was the most frequent bacterium isolated from UCs; however, in 10/16 hospitals and in 6/15 community settings, E. coli was isolated in less than 50 % of the total positive UCs. Other bacterial strains were Klebsiella, Enterococcus, Proteus and Pseudomonas not only from hospital settings. E. coli showed a high resistance to amoxicillin and trimethoprim and variable to cephalosporin. Nitrofurantoin had a good rate of efficacy, with 11/16 hospitals and 11/14 community settings reporting a resistance lower than 5 %. Conclusion: E. coli is the most common organism causing UTIs in infants; however, other bacterial strains are frequently isolated. As a result, antibiotic prophylaxis should be more elastic and adaptable over time in order to guarantee maximum efficacy.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Alberici, Irene UNSPECIFIED UNSPECIFIED UNSPECIFIED Bayazit, Aysun Karabay UNSPECIFIED UNSPECIFIED UNSPECIFIED Drozdz, Dorota UNSPECIFIED UNSPECIFIED UNSPECIFIED Emre, Sevinc UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischbach, Michel UNSPECIFIED UNSPECIFIED UNSPECIFIED Harambat, Jerome UNSPECIFIED UNSPECIFIED UNSPECIFIED Jankauskiene, Augustina UNSPECIFIED UNSPECIFIED UNSPECIFIED Litwin, Mieczyslaw UNSPECIFIED orcid.org/0000-0002-5241-2483 UNSPECIFIED Mir, Sevgi UNSPECIFIED UNSPECIFIED UNSPECIFIED Morello, William UNSPECIFIED orcid.org/0000-0002-4833-4128 UNSPECIFIED Peco-Antic, Amira UNSPECIFIED UNSPECIFIED UNSPECIFIED Sallay, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Sever, Lale UNSPECIFIED UNSPECIFIED UNSPECIFIED Simonetti, Giacomo D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Szczesniak, Przemyslaw UNSPECIFIED UNSPECIFIED UNSPECIFIED Teixeira, Ana UNSPECIFIED UNSPECIFIED UNSPECIFIED Vidal, Enrico UNSPECIFIED orcid.org/0000-0003-3963-0803 UNSPECIFIED Wuehl, Elke UNSPECIFIED UNSPECIFIED UNSPECIFIED Mehls, Otto UNSPECIFIED UNSPECIFIED UNSPECIFIED Weber, Lutz T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaefer, Franz UNSPECIFIED UNSPECIFIED UNSPECIFIED Montini, Giovanni UNSPECIFIED orcid.org/0000-0002-7350-4475 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-403024
DOI:	10.1007/s00431-014-2459-3
Journal or Publication Title:	Eur. J. Pediatr.
Volume:	174
Number:	6
Page Range:	S. 783 - 791
Date:	2015
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1076
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ANTIBIOTIC-RESISTANCE; ANTIMICROBIAL RESISTANCE; ESCHERICHIA-COLI; VESICOURETERAL REFLUX; TURKISH CHILDREN; YOUNG-CHILDREN; SUSCEPTIBILITY; UROPATHOGENS; PREVALENCE; PATTERNS Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/40302