Universität zu Köln

Marquardt, Philipp, Krause, Rolfdieter, Schaller, Mathias, Bach, Dieter and von Gersdorff, Gero (2015). Vitamin D Status and Cancer Prevalence of Hemodialysis Patients in Germany. Anticancer Res., 35 (2). S. 1182 - 1189. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7530

Full text not available from this repository.

Abstract

Aim: To describe Vitamin D (VitD) status and prevalence of cancer in a large cohort of ambulatory hemodialysis patients in Germany. Patients and Methods: In a registry study adult patients starting dialysis between 2006 and 2012 were analyzed for VitD blood levels and International classification of diseases (ICD)-10 cancer diagnoses. Results: Almost one third (32.7%) of patients initiating dialysis, had VitD levels <12.5 ng/ml and 79.7% had levels <30 ng/ml (n=8,377). Average VitD at dialysis initiation increased from 18.0 to 23.2 ng/ml between 2006 and 2012. Prevalence of cancer in this cohort was 22.1% with genital, renal and gastro-intestinal cancers being most common. Cancer frequencies were similar in patients with high and low vitamin D levels. Conclusion: Most chronic hemodialysis patients were vitamin D-deficient in spite of concurrent vitamin D supplementation. The burden of cancer was high in these patients. Future studies should address the role of vitamin D treatment on the course and progression of cancer in chronic kidney disease (CKD) patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Marquardt, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Krause, Rolfdieter UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaller, Mathias UNSPECIFIED UNSPECIFIED UNSPECIFIED Bach, Dieter UNSPECIFIED UNSPECIFIED UNSPECIFIED von Gersdorff, Gero UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-413221
Journal or Publication Title:	Anticancer Res.
Volume:	35
Number:	2
Page Range:	S. 1182 - 1189
Date:	2015
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7530
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language D DEFICIENCY; RISK; MORTALITY; DIALYSIS; OUTCOMES; CALCIUM; DISEASE; CKD Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41322