Universität zu Köln

Timmermann, L., Eggers, C., Dafsari, H. Salimi, Pauls, K. A. M. and Barbe, M. T. (2012). Parkinson's Disease: Current Standards in Diagnostics and Therapy. Forschritte Neurol. Psychiatr., 80 (10). S. 560 - 570. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3522

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Abstract

Idiopathic Parkinson's disease is still a clinical diagnosis. However, modern imaging and nuclear techniques allow very early diagnosis and lead to higher security in the differential diagnosis between idiopathic Parkinson's disease and atypical Parkinson syndromes. At early stages of the disease, modification of disease progression and symptom control are key factors of the therapy. Continuous dopaminergic stimulation is even more important at later stages with first fluctuations. In stages where conservative medical options have been exhausted continuous pump therapies with Duodopa and apomorphine are attractive options. Deep brain stimulation in the subthalamic nucleus has turned out in the last years, especially in younger patients, to be a highly successful treatment option. Deep drain stimulation requires, however, a close preoperative work-up and individual consideration of potential effects and side effects.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Timmermann, L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Eggers, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dafsari, H. Salimi UNSPECIFIED UNSPECIFIED UNSPECIFIED Pauls, K. A. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Barbe, M. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-481390
DOI:	10.1055/s-0032-1312738
Journal or Publication Title:	Forschritte Neurol. Psychiatr.
Volume:	80
Number:	10
Page Range:	S. 560 - 570
Date:	2012
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-3522
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DEEP-BRAIN-STIMULATION; SUBCUTANEOUS APOMORPHINE INFUSION; DUODENAL LEVODOPA INFUSION; DOUBLE-BLIND; MOTOR; EFFICACY; PEDUNCULOPONTINE; RASAGILINE; SYMPTOMS; DEMENTIA Multiple languages Clinical Neurology; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48139