Universität zu Köln

Kuhn, J., Bartsch, C., Lenartz, D., Huys, D., Daumann, J., Woopen, C., Hunsche, S., Maarouf, M., Klosterkoetter, J. and Sturm, V. (2011). Clinical effectiveness of unilateral deep brain stimulation in Tourette syndrome. Transl. Psychiatr., 1. LONDON: NATURE PUBLISHING GROUP. ISSN 2158-3188

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Abstract

Dysfunctional basal ganglia loops are thought to underlie the clinical picture of Tourette syndrome (TS). By altering dopaminergic activity in the affected neural structures, bilateral deep brain stimulation is assumed to have a modulatory effect on dopamine transmission resulting in an amelioration of tics. While the majority of published case reports deals with the application of bilateral stimulation, the present study aims at informing about the high effectiveness of unilateral stimulation of pallidal and nigral thalamic territories in TS. Potential implications and gains of the unilateral approach are discussed. Translational Psychiatry (2011) 1, e52; doi: 10.1038/tp.2011.51; published online 15 November 2011

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kuhn, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bartsch, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lenartz, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Huys, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Daumann, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Woopen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hunsche, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maarouf, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sturm, V. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-485605
DOI:	10.1038/tp.2011.51
Journal or Publication Title:	Transl. Psychiatr.
Volume:	1
Date:	2011
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	2158-3188
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NUCLEUS-ACCUMBENS Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48560