Rose, Michael, Haider, Hilde, Salari, Neda and Buechel, Christian (2011). Functional Dissociation of Hippocampal Mechanism during Implicit Learning Based on the Domain of Associations. J. Neurosci., 31 (39). S. 13739 - 13746. WASHINGTON: SOC NEUROSCIENCE. ISSN 1529-2401

Full text not available from this repository.

Abstract

Traditionally, the medial temporal lobe (MTL) was linked to explicit or declarative memory in associative learning. However, recent studies have reported MTL involvement even when volunteers are not consciously aware of the learned contingencies. Therefore, the mechanism of the MTL-related learning process cannot be described sufficiently by the explicit/implicit distinction, and the underlying process in the MTL for associative learning needs a more functional characterization. A possible feature that would allow a functional specification also for implicit learning is the nature of the material that is learned. Given that implicit memory tasks often comprise a combination of perceptual and motor learning, we hypothesized that implicit learning of the perceptual but not the motor component entails MTL activation in these studies. To directly test this hypothesis, we designed a purely perceptual and a purely motor variant of the serial reaction time task. In two groups of human volunteers, behavioral results clearly showed that both variants were learned without awareness. Neuronal recordings using fMRI revealed that bilateral hippocampal activation was observed only for implicit learning of the perceptual sequence, not for the motor sequence. This dissociation clearly shows that the functional role of the hippocampus for learning is determined by the domain of the learned association and that the function of the medial temporal lobe system is the processing of contingencies between perceptual features regardless of the explicit or implicit nature of the ensuing memory.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Rose, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haider, HildeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Salari, NedaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buechel, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-488823
DOI: 10.1523/JNEUROSCI.3020-11.2011
Journal or Publication Title: J. Neurosci.
Volume: 31
Number: 39
Page Range: S. 13739 - 13746
Date: 2011
Publisher: SOC NEUROSCIENCE
Place of Publication: WASHINGTON
ISSN: 1529-2401
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MEDIAL TEMPORAL-LOBE; DECLARATIVE MEMORY; PERIRHINAL CORTEX; SEQUENCES; SYSTEMS; INFORMATION; TACTILEMultiple languages
NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/48882

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item