Universität zu Köln

Bevers, Loes E., Schwarz, Guenter ORCID: 0000-0002-2118-9338 and Hagen, Wilfred R. ORCID: 0000-0002-1609-6671 (2011). A Molecular Basis for Tungstate Selectivity in Prokaryotic ABC Transport Systems. J. Bacteriol., 193 (18). S. 4999 - 5002. WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 0021-9193

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Abstract

The essential trace compounds tungstate and molybdate are taken up by cells via ABC transporters. Despite their similar ionic radii and chemical properties, the WtpA protein selectively binds tungstate in the presence of molybdate. Using site-directed mutagenesis of conserved binding pocket residues, we established a molecular basis for tungstate selectivity.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bevers, Loes E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schwarz, Guenter UNSPECIFIED orcid.org/0000-0002-2118-9338 UNSPECIFIED Hagen, Wilfred R. UNSPECIFIED orcid.org/0000-0002-1609-6671 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-489961
DOI:	10.1128/JB.05056-11
Journal or Publication Title:	J. Bacteriol.
Volume:	193
Number:	18
Page Range:	S. 4999 - 5002
Date:	2011
Publisher:	AMER SOC MICROBIOLOGY
Place of Publication:	WASHINGTON
ISSN:	0021-9193
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MOLYBDATE-BINDING-PROTEIN; CRYSTAL-STRUCTURE; ESCHERICHIA-COLI; MODA Multiple languages Microbiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48996