Ma, Ka-Wai, Niu, Yulong, Jia, Yong, Ordon, Jana ORCID: 0000-0001-8764-6418, Copeland, Charles ORCID: 0000-0001-8535-8615, Emonet, Aurelia, Geldner, Niko ORCID: 0000-0002-2300-9644, Guan, Rui, Stolze, Sara Christina ORCID: 0000-0002-1421-9703, Nakagami, Hirofumi ORCID: 0000-0003-2569-7062, Garrido-Oter, Ruben and Schulze-Lefert, Paul (2021). Coordination of microbe-host homeostasis by crosstalk with plant innate immunity. Nat. Plants, 7 (6). S. 814 - 846. BERLIN: NATURE RESEARCH. ISSN 2055-0278

Full text not available from this repository.

Abstract

Plants grown in natural soil are colonized by phylogenetically structured communities of microbes known as the microbiota. Individual microbes can activate microbe-associated molecular pattern (MAMP)-triggered immunity (MTI), which limits pathogen proliferation but curtails plant growth, a phenomenon known as the growth-defence trade-off. Here, we report that, in monoassociations, 41% (62 out of 151) of taxonomically diverse root bacterial commensals suppress Arabidopsis thaliana root growth inhibition (RGI) triggered by immune-stimulating MAMPs or damage-associated molecular patterns. Amplicon sequencing of bacterial 16S rRNA genes reveals that immune activation alters the profile of synthetic communities (SynComs) comprising RGI-non-suppressive strains, whereas the presence of RGI-suppressive strains attenuates this effect. Root colonization by SynComs with different complexities and RGI-suppressive activities alters the expression of 174 core host genes, with functions related to root development and nutrient transport. Furthermore, RGI-suppressive SynComs specifically downregulate a subset of immune-related genes. Precolonization of plants with RGI-suppressive SynComs, or mutation of one commensal-downregulated transcription factor, MYB15, renders the plants more susceptible to opportunistic Pseudomonas pathogens. Our results suggest that RGI-non-suppressive and RGI-suppressive root commensals modulate host susceptibility to pathogens by either eliciting or dampening MTI responses, respectively. This interplay buffers the plant immune system against pathogen perturbation and defence-associated growth inhibition, ultimately leading to commensal-host homeostasis. Plants evolved powerful mechanisms to fight against pathogenic microorganisms. So how can they accept and even favour the presence of growth-promoting fungi or bacteria? Here, the authors show that helpful commensal bacteria can suppress part of the plant innate immune system.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Ma, Ka-WaiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Niu, YulongUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jia, YongUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ordon, JanaUNSPECIFIEDorcid.org/0000-0001-8764-6418UNSPECIFIED
Copeland, CharlesUNSPECIFIEDorcid.org/0000-0001-8535-8615UNSPECIFIED
Emonet, AureliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Geldner, NikoUNSPECIFIEDorcid.org/0000-0002-2300-9644UNSPECIFIED
Guan, RuiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stolze, Sara ChristinaUNSPECIFIEDorcid.org/0000-0002-1421-9703UNSPECIFIED
Nakagami, HirofumiUNSPECIFIEDorcid.org/0000-0003-2569-7062UNSPECIFIED
Garrido-Oter, RubenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schulze-Lefert, PaulUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-583022
DOI: 10.1038/s41477-021-00920-2
Journal or Publication Title: Nat. Plants
Volume: 7
Number: 6
Page Range: S. 814 - 846
Date: 2021
Publisher: NATURE RESEARCH
Place of Publication: BERLIN
ISSN: 2055-0278
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ARABIDOPSIS-THALIANA; ROOT MICROBIOTA; RESPONSES; GROWTH; ACID; RESISTANCE; EXPRESSION; NUTRITION; PATTERNS; PACKAGEMultiple languages
Plant SciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58302

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item