Ourry, Valentin ORCID: 0000-0002-8535-9009, Marchant, Natalie L., Schild, Ann-Katrin, Coll-Padros, Nina ORCID: 0000-0002-9282-6701, Klimecki, Olga M., Krolak-Salmon, Pierre, Goldet, Karine, Reyrolle, Leslie, Bachelet, Romain, Sannemann, Lena, Meiberth, Dix, Demnitz-King, Harriet, Whitfield, Tim, Botton, Maelle, Lebahar, Julie, Gonneaud, Julie ORCID: 0000-0003-0566-5581, de Flores, Robin ORCID: 0000-0003-3953-3392, Molinuevo, Jose Luis, Jessen, Frank, Vivien, Denis, De la Sayette, Vincent, Valenzuela, Michael J., Rauchs, Geraldine, Wirth, Miranka, Chetelat, Gael and Arenaza-Urquijo, Eider M. (2021). Harmonisation and Between-Country Differences of the Lifetime of Experiences Questionnaire in Older Adults. Front. Aging Neurosci., 13. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1663-4365

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Abstract

Background: The Lifetime of Experiences Questionnaire (LEQ) assesses complex mental activity across the life-course and has been associated with brain and cognitive health. The different education systems and occupation classifications across countries represent a challenge for international comparisons. The objectives of this study were four-fold: to adapt and harmonise the LEQ across four European countries, assess its validity across countries, explore its association with brain and cognition and begin to investigate between-country differences in life-course mental activities.</p> Method: The LEQ was administered to 359 cognitively unimpaired older adults (mean age and education: 71.2, 13.2 years) from IMAP and EU-funded Medit-Ageing projects. Education systems, classification of occupations and scoring guidelines were adapted to allow comparisons between France, Germany, Spain and United Kingdom. We assessed the LEQ's (i) concurrent validity with a similar instrument (cognitive activities questionnaire - CAQ) and its structural validity by testing the factors' structure across countries, (ii) we investigated its association with cognition and neuroimaging, and (iii) compared its scores between countries.</p> Results: The LEQ showed moderate to strong positive associations with the CAQ and revealed a stable multidimensional structure across countries that was similar to the original LEQ. The LEQ was positively associated with global cognition. Between-country differences were observed in leisure activities across the life-course.</p> Conclusions: The LEQ is a promising tool for assessing the multidimensional construct of cognitive reserve and can be used to measure socio-behavioural determinants of cognitive reserve in older adults across countries. Longitudinal studies are warranted to test further its clinical utility.</p>

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Ourry, ValentinUNSPECIFIEDorcid.org/0000-0002-8535-9009UNSPECIFIED
Marchant, Natalie L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schild, Ann-KatrinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Coll-Padros, NinaUNSPECIFIEDorcid.org/0000-0002-9282-6701UNSPECIFIED
Klimecki, Olga M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krolak-Salmon, PierreUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goldet, KarineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reyrolle, LeslieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bachelet, RomainUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sannemann, LenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meiberth, DixUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Demnitz-King, HarrietUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Whitfield, TimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Botton, MaelleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lebahar, JulieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gonneaud, JulieUNSPECIFIEDorcid.org/0000-0003-0566-5581UNSPECIFIED
de Flores, RobinUNSPECIFIEDorcid.org/0000-0003-3953-3392UNSPECIFIED
Molinuevo, Jose LuisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jessen, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vivien, DenisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
De la Sayette, VincentUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Valenzuela, Michael J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rauchs, GeraldineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wirth, MirankaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chetelat, GaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arenaza-Urquijo, Eider M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-603088
DOI: 10.3389/fnagi.2021.740005
Journal or Publication Title: Front. Aging Neurosci.
Volume: 13
Date: 2021
Publisher: FRONTIERS MEDIA SA
Place of Publication: LAUSANNE
ISSN: 1663-4365
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SUBJECTIVE COGNITIVE DECLINE; BRAIN RESERVE; DEMENTIA; EDUCATION; ATROPHY; VOLUMEMultiple languages
Geriatrics & Gerontology; NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60308

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