Mullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R., I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Borte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee ORCID: 0000-0001-5719-0552, Abramova, Liliya ORCID: 0000-0003-4397-924X, Adorjan, Kristina, Agerbo, Esben ORCID: 0000-0002-2849-524X, Al Eissa, Mariam, Albani, Diego, Alliey-Rodriguez, Ney, Anjorin, Adebayo, Antilla, Verneri, Antoniou, Anastasia, Awasthi, Swapnil ORCID: 0000-0002-9692-8123, Baek, Ji Hyun, Baekvad-Hansen, Marie, Bass, Nicholas, Bauer, Michael, Beins, Eva C., Bergen, Sarah E., Birner, Armin, Pedersen, Carsten Bocker, Boen, Erlend, Boks, Marco P., Bosch, Rosa ORCID: 0000-0002-7596-183X, Brum, Murielle, Brumpton, Ben M., Brunkhorst-Kanaan, Nathalie, Budde, Monika, Bybjerg-Grauholm, Jonas, Byerley, William, Cairns, Murray, Casas, Miquel, Cervantes, Pablo, Clarke, Toni-Kim ORCID: 0000-0002-7745-6351, Cruceanu, Cristiana ORCID: 0000-0002-7799-5531, Cuellar-Barboza, Alfredo ORCID: 0000-0002-7663-913X, Cunningham, Julie, Curtis, David, Czerski, Piotr M., Dale, Anders M., Dalkner, Nina, David, Friederike S., Degenhardt, Franziska, Djurovic, Srdjan, Dobbyn, Amanda L., Douzenis, Athanassios, Elvsashagen, Torbjorn, Escott-Price, Valentina ORCID: 0000-0003-1784-5483, Ferrier, I. Nicol, Fiorentino, Alessia, Foroud, Tatiana M., Forty, Liz, Frank, Josef, Frei, Oleksandr, Freimer, Nelson B., Frisen, Louise, Gade, Katrin, Garnham, Julie, Gelernter, Joel, Pedersen, Marianne Giortz, Gizer, Ian R., Gordon, Scott D., Gordon-Smith, Katherine, Greenwood, Tiffany A., Grove, Jakob ORCID: 0000-0003-2284-5744, Guzman-Parra, Jose ORCID: 0000-0002-1463-6435, Ha, Kyooseob, Haraldsson, Magnus, Hautzinger, Martin, Heilbronner, Urs ORCID: 0000-0001-7135-762X, Hellgren, Dennis, Herms, Stefan, Hoffmann, Per, Holmans, Peter A., Huckins, Laura, Jamain, Stephane, Johnson, Jessica S., Kalman, Janos L., Kamatani, Yoichiro, Kennedy, James L., Kittel-Schneider, Sarah, Knowles, James A., Kogevinas, Manolis, Koromina, Maria, Kranz, Thorsten M., Kranzler, Henry R., Kubo, Michiaki, Kupka, Ralph, Kushner, Steven A., Lavebratt, Catharina, Lawrence, Jacob, Leber, Markus, Lee, Heon-Jeong, Lee, Phil H., Levy, Shawn E., Lewis, Catrin, Liao, Calwing, Lucae, Susanne, Lundberg, Martin, MacIntyre, Donald J., Maier, Wolfgang, Maihofer, Adam, Malaspina, Dolores, Maratou, Eirini, Martinsson, Lina, Mattheisen, Manuel ORCID: 0000-0002-8442-493X, McCarroll, Steven A., McGregor, Nathaniel W., McGuffin, Peter, McKay, James D., Medeiros, Helena, Medland, Sarah E., Millischer, Vincent ORCID: 0000-0003-1919-9649, Montgomery, Grant W., Moran, Jennifer L., Morris, Derek W., Muhleisen, Thomas W., O'Brien, Niamh, O'Donovan, Claire, Loohuis, Loes M. Olde, Oruc, Lilijana, Papiol, Sergi, Pardinas, Antonio F., Perry, Amy, Pfennig, Andrea, Porichi, Evgenia, Potash, James B., Quested, Digby, Raj, Towfique, Rapaport, Mark H., DePaulo, J. Raymond, Regeer, Eline J., Rice, John P., Rivas, Fabio, Rivera, Margarita ORCID: 0000-0003-4717-1045, Roth, Julian, Roussos, Panos, Ruderfer, Douglas M., Sanchez-Mora, Cristina, Schulte, Eva C., Senner, Fanny, Sharp, Sally, Shilling, Paul D., Sigurdsson, Engilbert ORCID: 0000-0001-9404-7982, Sirignano, Lea, Slaney, Claire, Smeland, Olav B., Sobell, Janet L., Hansen, Christine Soholm, Artigas, Maria Soler, Spijker, Anne T., Stein, Dan J., Strauss, John S., Swiatkowska, Beata ORCID: 0000-0003-3757-3868, Terao, Chikashi, Thorgeirsson, Thorgeir E., Toma, Claudio ORCID: 0000-0003-3901-7507, Tooney, Paul ORCID: 0000-0003-3745-4367, Tsermpini, Evangelia-Eirini, Vawter, Marquis P., Vedder, Helmut, Walters, James T. R., Witt, Stephanie H., Xi, Simon, Xu, Wei, Yang, Jessica Mei Kay, Young, Allan H., Young, Hannah, Zandi, Peter P., Zhou, Hang, Zillich, Lea, Adolfsson, Rolf, Agartz, Ingrid, Alda, Martin, Alfredsson, Lars, Babadjanova, Gulja, Backlund, Lena, Baune, Bernhard T., Bellivier, Frank, Bengesser, Susanne, Berrettini, Wade H., Blackwood, Douglas H. R., Boehnke, Michael, Borglum, Anders D., Breen, Gerome ORCID: 0000-0003-2053-1792, Carr, Vaughan J., Catts, Stanley, Corvin, Aiden, Craddock, Nicholas, Dannlowski, Udo, Dikeos, Dimitris, Esko, Tonu, Etain, Bruno, Ferentinos, Panagiotis ORCID: 0000-0001-8531-5623, Frye, Mark, Fullerton, Janice M., Gawlik, Micha, Gershon, Elliot S., Goes, Fernando, Green, Melissa J., Grigoroiu-Serbanescu, Maria ORCID: 0000-0002-1304-6687, Hauser, Joanna, Henskens, Frans, Hillert, Jan, Hong, Kyung Sue, Hougaard, David M., Hultman, Christina M., Hveem, Kristian, Iwata, Nakao, Jablensky, Assen, V, Jones, Ian, Jones, Lisa A., Kahn, Rene S., Kelsoe, John R., Kirov, George, Landen, Mikael, Leboyer, Marion ORCID: 0000-0001-5473-3697, Lewis, Cathryn M., Li, Qingqin S., Lissowska, Jolanta ORCID: 0000-0003-2695-5799, Lochner, Christine, Loughland, Carmel, Martin, Nicholas G., Mathews, Carol A., Mayoral, Fermin, McElroy, Susan L., McIntosh, Andrew M., McMahon, Francis J., Melle, Ingrid, Michie, Patricia, Milani, Lili, Mitchell, Philip B., Morken, Gunnar, Mors, Ole, Mortensen, Preben Bo, Mowry, Bryan ORCID: 0000-0002-4115-5645, Muller-Myhsok, Bertram, Myers, Richard M., Neale, Benjamin M., Nievergelt, Caroline M., Nordentoft, Merete, Nothen, Markus M., ODonovan, Michael C., Oedegaard, Ketil J., Olsson, Tomas, Owen, Michael J., Paciga, Sara A., Pantelis, Chris, Pato, Carlos, Pato, Michele T., Patrinos, George P., Perlis, Roy H., Posthuma, Danielle ORCID: 0000-0001-7582-2365, Ramos-Quiroga, Josep Antoni, Reif, Andreas, Reininghaus, Eva Z., Ribases, Marta, Rietschel, Marcella, Ripke, Stephan, Rouleau, Guy A., Saito, Takeo, Schall, Ulrich, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Scott, Laura J., Scott, Rodney J., Serretti, Alessandro, Weickert, Cynthia Shannon, Smoller, Jordan W., Stefansson, Hreinn, Stefansson, Kari, Stordal, Eystein, Streit, Fabian, Sullivan, Patrick F., Turecki, Gustavo, Vaaler, Arne E., Vieta, Eduard ORCID: 0000-0002-0548-0053, Vincent, John B., Waldman, Irwin D., Weickert, Thomas W., Werge, Thomas, Wray, Naomi R., Zwart, JohnAnker, Biernacka, Joanna M., Nurnberger, John, I, Cichon, Sven, Edenberg, Howard J., Stahl, Eli A., McQuillin, Andrew ORCID: 0000-0003-1567-2240, Di Florio, Arianna, Ophoff, Roel A. and Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genet., 53 (6). S. 817 - 836. BERLIN: NATURE PORTFOLIO. ISSN 1546-1718

Full text not available from this repository.

Abstract

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci. Bipolar disorder risk alleles were enriched in genes in synaptic signaling pathways and brain-expressed genes, particularly those with high specificity of expression in neurons of the prefrontal cortex and hippocampus. Significant signal enrichment was found in genes encoding targets of antipsychotics, calcium channel blockers, antiepileptics and anesthetics. Integrating expression quantitative trait locus data implicated 15 genes robustly linked to bipolar disorder via gene expression, encoding druggable targets such as HTR6, MCHR1, DCLK3 and FURIN. Analyses of bipolar disorder subtypes indicated high but imperfect genetic correlation between bipolar disorder type I and II and identified additional associated loci. Together, these results advance our understanding of the biological etiology of bipolar disorder, identify novel therapeutic leads and prioritize genes for functional follow-up studies. Genome-wide association analyses of 41,917 bipolar disorder cases and 371,549 controls of European ancestry provide new insights into the etiology of this disorder and identify novel therapeutic leads and potential opportunities for drug repurposing.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Mullins, NiamhUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Forstner, Andreas J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
O'Connell, Kevin S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Coombes, BrandonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Coleman, Jonathan R., IUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Qiao, ZhenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Als, Thomas D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bigdeli, Tim B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borte, SigridUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bryois, JulienUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Charney, Alexander W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Drange, Ole KristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gandal, Michael J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hagenaars, Saskia P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ikeda, MasashiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kamitaki, NolanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kim, MinsooUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krebs, KristiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Panagiotaropoulou, GeorgiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schilder, Brian M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sloofman, Laura G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steinberg, StacyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Trubetskoy, VassilyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Winsvold, Bendik S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Won, Hong-HeeUNSPECIFIEDorcid.org/0000-0001-5719-0552UNSPECIFIED
Abramova, LiliyaUNSPECIFIEDorcid.org/0000-0003-4397-924XUNSPECIFIED
Adorjan, KristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Agerbo, EsbenUNSPECIFIEDorcid.org/0000-0002-2849-524XUNSPECIFIED
Al Eissa, MariamUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Albani, DiegoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Alliey-Rodriguez, NeyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Anjorin, AdebayoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Antilla, VerneriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Antoniou, AnastasiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Awasthi, SwapnilUNSPECIFIEDorcid.org/0000-0002-9692-8123UNSPECIFIED
Baek, Ji HyunUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baekvad-Hansen, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bass, NicholasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bauer, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beins, Eva C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bergen, Sarah E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Birner, ArminUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pedersen, Carsten BockerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boen, ErlendUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boks, Marco P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bosch, RosaUNSPECIFIEDorcid.org/0000-0002-7596-183XUNSPECIFIED
Brum, MurielleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brumpton, Ben M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brunkhorst-Kanaan, NathalieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Budde, MonikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bybjerg-Grauholm, JonasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Byerley, WilliamUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cairns, MurrayUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Casas, MiquelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cervantes, PabloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Clarke, Toni-KimUNSPECIFIEDorcid.org/0000-0002-7745-6351UNSPECIFIED
Cruceanu, CristianaUNSPECIFIEDorcid.org/0000-0002-7799-5531UNSPECIFIED
Cuellar-Barboza, AlfredoUNSPECIFIEDorcid.org/0000-0002-7663-913XUNSPECIFIED
Cunningham, JulieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Curtis, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Czerski, Piotr M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dale, Anders M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dalkner, NinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
David, Friederike S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Degenhardt, FranziskaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Djurovic, SrdjanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dobbyn, Amanda L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Douzenis, AthanassiosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Elvsashagen, TorbjornUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Escott-Price, ValentinaUNSPECIFIEDorcid.org/0000-0003-1784-5483UNSPECIFIED
Ferrier, I. NicolUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fiorentino, AlessiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Foroud, Tatiana M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Forty, LizUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frank, JosefUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frei, OleksandrUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Freimer, Nelson B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frisen, LouiseUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gade, KatrinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Garnham, JulieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gelernter, JoelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pedersen, Marianne GiortzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gizer, Ian R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gordon, Scott D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gordon-Smith, KatherineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Greenwood, Tiffany A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Guzman-Parra, JoseUNSPECIFIEDorcid.org/0000-0002-1463-6435UNSPECIFIED
Ha, KyooseobUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haraldsson, MagnusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hautzinger, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heilbronner, UrsUNSPECIFIEDorcid.org/0000-0001-7135-762XUNSPECIFIED
Hellgren, DennisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Holmans, Peter A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huckins, LauraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jamain, StephaneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Johnson, Jessica S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kalman, Janos L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Kranz, Thorsten M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
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Melle, IngridUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Michie, PatriciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Milani, LiliUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mitchell, Philip B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Morken, GunnarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mors, OleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mortensen, Preben BoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mowry, BryanUNSPECIFIEDorcid.org/0000-0002-4115-5645UNSPECIFIED
Muller-Myhsok, BertramUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Myers, Richard M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neale, Benjamin M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nievergelt, Caroline M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nordentoft, MereteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nothen, Markus M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
ODonovan, Michael C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Oedegaard, Ketil J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olsson, TomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Owen, Michael J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paciga, Sara A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pantelis, ChrisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pato, CarlosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pato, Michele T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Patrinos, George P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Perlis, Roy H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Posthuma, DanielleUNSPECIFIEDorcid.org/0000-0001-7582-2365UNSPECIFIED
Ramos-Quiroga, Josep AntoniUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reif, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reininghaus, Eva Z.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ribases, MartaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rietschel, MarcellaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ripke, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rouleau, Guy A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Saito, TakeoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schall, UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schalling, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schofield, Peter R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schulze, Thomas G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scott, Laura J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scott, Rodney J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Serretti, AlessandroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weickert, Cynthia ShannonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Smoller, Jordan W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stefansson, HreinnUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stefansson, KariUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stordal, EysteinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Streit, FabianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sullivan, Patrick F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Turecki, GustavoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vaaler, Arne E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vieta, EduardUNSPECIFIEDorcid.org/0000-0002-0548-0053UNSPECIFIED
Vincent, John B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Waldman, Irwin D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weickert, Thomas W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Werge, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wray, Naomi R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zwart, JohnAnkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Biernacka, Joanna M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nurnberger, John, IUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cichon, SvenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Edenberg, Howard J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stahl, Eli A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McQuillin, AndrewUNSPECIFIEDorcid.org/0000-0003-1567-2240UNSPECIFIED
Di Florio, AriannaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ophoff, Roel A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Andreassen, Ole A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-608522
DOI: 10.1038/s41588-021-00857-4
Journal or Publication Title: Nature Genet.
Volume: 53
Number: 6
Page Range: S. 817 - 836
Date: 2021
Publisher: NATURE PORTFOLIO
Place of Publication: BERLIN
ISSN: 1546-1718
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
LD SCORE REGRESSION; EDUCATIONAL-ATTAINMENT; GENOTYPE IMPUTATION; SPECTRUM DISORDER; RISK; SCHIZOPHRENIA; PREVALENCE; LOCI; IDENTIFICATION; POLYGENICITYMultiple languages
Genetics & HeredityMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60852

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