Safety Evaluations Under the Proposed US Safe Cosmetics and Personal Care Products Act of 2013 : Animal Use and Cost Estimates

Knight, Jean; Rovida, Costanza

Safety Evaluations Under the Proposed US Safe Cosmetics and Personal Care Products Act of 2013 : Animal Use and Cost Estimates

Dateien

Knight_0-275000.pdfGröße: 323.32 KBDownloads: 892

Datum

2014

Autor:innen

Knight, Jean

Rovida, Costanza

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Alternatives to Animal Experimentation : ALTEX. 2014, 31(2), pp. 177-208. ISSN 0946-7785. eISSN 1868-8551. Available under: doi: 10.14573/altex.1309271

Zusammenfassung

The proposed Safe Cosmetics and Personal Care Products Act of 2013 calls for a new evaluation program for cosmetic ingredients in the US, with the new assessments initially dependent on expanded animal testing. This paper considers possible testing scenarios under the proposed Act and estimates the number of test animals and cost under each scenario. It focuses on the impact for the first 10 years of testing, the period of greatest impact on animals and costs. The analysis suggests the first 10 years of testing under the Act could evaluate, at most, about 50% of ingredients used in cosmetics. Testing during this period would cost about $ 1.7-$ 9 billion and 1-11.5 million animals. By test year 10, alternative, high-throughput test methods under development are expected to be available, replacing animal testing and allowing rapid evaluation of all ingredients. Given the high cost in dollars and animal lives of the first 10 years for only about half of ingredients, a better choice may be to accelerate development of high-throughput methods. This would allow evaluation of 100% of cosmetic ingredients before year 10 at lower cost and without animal testing.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

Safe Cosmetics and Personal Care Products Act of 2013/H.R. 1385, animal testing, alternative test methods, cosmetics safety

Zitieren

ISO 690

KNIGHT, Jean, Costanza ROVIDA, 2014. Safety Evaluations Under the Proposed US Safe Cosmetics and Personal Care Products Act of 2013 : Animal Use and Cost Estimates. In: Alternatives to Animal Experimentation : ALTEX. 2014, 31(2), pp. 177-208. ISSN 0946-7785. eISSN 1868-8551. Available under: doi: 10.14573/altex.1309271

BibTex

@article{Knight2014Safet-30421,
  year={2014},
  doi={10.14573/altex.1309271},
  title={Safety Evaluations Under the Proposed US Safe Cosmetics and Personal Care Products Act of 2013 : Animal Use and Cost Estimates},
  number={2},
  volume={31},
  issn={0946-7785},
  journal={Alternatives to Animal Experimentation : ALTEX},
  pages={177--208},
  author={Knight, Jean and Rovida, Costanza}
}

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